Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | FLT1 | P17948 | 1/20 | 0.41 |
| ▸ | FLT4 | P35916 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7867914 | 0.93 | SMN1; SMN2 (0.46) | MAPTPPARAEGFRNPC1RAB9A | |
| SCHEMBL7862782 | 0.92 | RAB9A (0.49) | AKR1C3NPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL7874565 | 0.92 | PPARA (0.46) | AKR1C3MAPTPPARAEGFRNPC1 | |
| SCHEMBL7870522 | 0.92 | NPC1 (0.44) | MAPTNPC1RAB9ASMN1; SMN2GABRA5 | |
| SCHEMBL7874505 | 0.91 | EGFR (0.53) | MAPTPPARAEGFRNPC1RAB9A | |
| SCHEMBL7862777 | 0.91 | EGFR (0.53) | MAPTPPARAEGFRNPC1RAB9A | |
| SCHEMBL7870457 | 0.90 | SMN1; SMN2 (0.53) | AKR1C3MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8869195 | 0.90 | MAPT (0.50) | AKR1C3MAPTPPARAEGFRNPC1 | |
| SCHEMBL9018119 | 0.88 | PPARA (0.49) | AKR1C3MAPTPPARAEGFRNPC1 | |
| SCHEMBL7869411 | 0.88 | RAB9A (0.48) | MAPTNPC1RAB9ASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0562512-B1 | Sulfonamidocarbonylpyridine-2-carboxamides and their use as medicines | HOECHST AG (DE) | 2001-02-21 | — | — | EP | disclosed |
| EP-0562512-A1 | Sulfonamido- and sulfonamidocarbonyl-pyridine-2-carboxamides and their pyridine-N-oxides, process for their preparation and their use as medicines | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-09-29 | — | — | EP | disclosed |