Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Terephthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.71 |
| ▸ | TP53 | P04637 | 1/20 | 0.71 |
| ▸ | SRD5A2 | P31213 | 4/20 | 0.60 |
| ▸ | CA1 | P00915 | 2/20 | 0.57 |
| ▸ | CA2 | P00918 | 2/20 | 0.57 |
| ▸ | CA12 | O43570 | 1/20 | 0.57 |
| ▸ | CA3 | P07451 | 1/20 | 0.57 |
| ▸ | TYR | P14679 | 1/20 | 0.57 |
| ▸ | DRD1 | P21728 | 1/20 | 0.57 |
| ▸ | CA4 | P22748 | 1/20 | 0.57 |
| ▸ | CA6 | P23280 | 1/20 | 0.57 |
| ▸ | CA5A | P35218 | 1/20 | 0.57 |
| ▸ | CA7 | P43166 | 1/20 | 0.57 |
| ▸ | CA9 | Q16790 | 1/20 | 0.57 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.57 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | DAO | P14920 | 1/20 | 0.55 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Terephthalic Acid SCHEMBL540691 | 1.00 | TSHR (0.71) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL332989 | 0.88 | TSHR (0.71) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL31456604 | 0.86 | TSHR (0.67) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL28737896 | 0.86 | TSHR (0.67) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL19025074 | 0.86 | TSHR (0.67) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL9501513 | 0.86 | TSHR (0.67) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL16470220 | 0.86 | TSHR (0.67) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL15050 | 0.86 | TSHR (0.67) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL8211964 | 0.86 | TSHR (0.67) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL28022775 | 0.86 | TSHR (0.67) | TSHRTP53SRD5A2CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019053392-A1 | ENZYMATIC PROCESS FOR DEPOLYMERIZATION OF POST-CONSUMER POLY(ETHYLENE TEREPHTHALATE) BY A GLYCOLYSIS REACTION, PROCESS FOR RECYCLING POST-CONSUMER POLY(ETHYLENE TEREPHTHALATE) AND RECYCLED POLY(ETHYLENE TEREPHTHALATE) | Petróleo Brasileiro S.A. - Petrobras (BR) | 2019-03-21 | — | — | WO | claimed |
| CN-2460292-Y | Magnesium alloy product coated with color film | LIAO RIXING (CN) | 2001-11-21 | — | — | CN | claimed |
| WO-2023228034-A1 | CATALYST AND PROCESS FOR OBTAINING BHET FROM PET | INGBIOCOMB SAS (CO) | 2023-11-30 | — | — | WO | disclosed |
| CN-116555222-A | 2-hydroxyethyl terephthalic acid diester hydrolase mutant, encoding gene, recombinant vector, recombinant strain, enzyme preparation and application | 南京师范大学 | 2023-08-08 | — | — | CN | disclosed |
| CN-112176453-B | Four-leaf skin-core structure negative oxygen ion polyester fiber and preparation method thereof | 江苏家来福纺织有限公司 | 2021-11-16 | — | — | CN | disclosed |
| CN-112176453-B | Four-leaf skin-core structure negative oxygen ion polyester fiber and preparation method thereof | 江苏家来福纺织有限公司 | 2021-11-16 | — | — | CN | disclosed |
| US-11065098-B2 | Medical fabric | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2021-07-20 | — | — | US | disclosed |
| US-20210177568-A1 | Medical Fabric | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2021-06-17 | — | — | US | disclosed |
| US-20210054545-A1 | Medical Fabric | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2021-02-25 | — | — | US | disclosed |
| CN-112176453-A | Four-leaf skin-core structure negative oxygen ion polyester fiber and preparation method thereof | 江苏家来福纺织有限公司 | 2021-01-05 | — | — | CN | disclosed |
| CN-112176453-A | Four-leaf skin-core structure negative oxygen ion polyester fiber and preparation method thereof | 江苏家来福纺织有限公司 | 2021-01-05 | — | — | CN | disclosed |
| EP-0707562-B1 | PRODUCTION OF DICARBOXYLIC ACIDS | DU PONT (US) | 2000-04-26 | — | — | EP | disclosed |
| US-5886057-A | COMMINUTING SOLID POLYESTER, REACTING COMMINUTED POLYESTER WITH DIOL IN THE ABSENCE OF WATER AT A POLYESTER:DIOL RATIO OF AT LEAST 1:1 BY WEIGHT, REMOVING DIOL FROM THE LIQUID PHASE MEDIUM, SUBJECTING LIQUID PHASE TO HYDROLYSIS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1999-03-23 | — | — | US | disclosed |
| EP-0707563-B1 | PRODUCTION OF DICARBOXYLIC ACIDS OR ESTERS THEREOF | DU PONT (US) | 1999-02-17 | — | — | EP | disclosed |
| US-5750776-A | DEPOLYMERIZATION OF SOLID PHASE POLYESTERS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1998-05-12 | — | — | US | disclosed |
| EP-0707562-A1 | PRODUCTION OF DICARBOXYLIC ACIDS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1996-04-24 | — | — | EP | disclosed |
| EP-0707563-A1 | PRODUCTION OF DICARBOXYLIC ACIDS OR ESTERS THEREOF | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1996-04-24 | — | — | EP | disclosed |
| WO-1995001954-A1 | PRODUCTION OF DICARBOXYLIC ACIDS OR ESTERS THEREOF | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1995-01-19 | — | — | WO | disclosed |
| WO-1995001953-A1 | PRODUCTION OF DICARBOXYLIC ACIDS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1995-01-19 | — | — | WO | disclosed |
| US-4096124-A | TEREPHTHALIC ACID, ETHYLENE GLYCOL, TWO-STAGE | MOBIL OIL CORPORATION (US) | 1978-06-20 | — | — | US | disclosed |