Terephthalic Acid

Terephthalic Acid

SCHEMBL15050

C=CC.O=C(O)c1ccc(C(=O)O)cc1

nearest known ligand 0.67

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

OPRM1

The experimentally established mechanism targets of Terephthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.67
TP53 P04637 1/20 0.67
ALDH1A1 P00352 4/20 0.59
SMN1; SMN2 Q16637 1/20 0.59
SRD5A2 P31213 4/20 0.57
CA1 P00915 3/20 0.55
CA2 P00918 3/20 0.55
CA12 O43570 1/20 0.55
CA3 P07451 1/20 0.55
TYR P14679 1/20 0.55
DRD1 P21728 1/20 0.55
CA4 P22748 1/20 0.55
CA6 P23280 1/20 0.55
CA5A P35218 1/20 0.55
CA7 P43166 1/20 0.55
CA9 Q16790 1/20 0.55
CA14 Q9ULX7 1/20 0.55
CA5B Q9Y2D0 1/20 0.55
DAO P14920 1/20 0.52
NAPRT Q6XQN6 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Terephthalic Acid SCHEMBL16470220 1.00 TSHR (0.67) TSHRTP53ALDH1A1SMN1; SMN2SRD5A2
Terephthalic Acid SCHEMBL28737896 1.00 TSHR (0.67) TSHRTP53ALDH1A1SMN1; SMN2SRD5A2
Terephthalic Acid SCHEMBL11664464 0.97 TSHR (0.63) TSHRTP53ALDH1A1SMN1; SMN2SRD5A2
4-Methylbenzoic Acid SCHEMBL14722440 0.91 ALDH1A1 (0.77) TSHRTP53ALDH1A1SMN1; SMN2SRD5A2
Paraben SCHEMBL10746206 0.91 CA2 (0.73) TSHRTP53ALDH1A1SMN1; SMN2SRD5A2
Benzoic Acid SCHEMBL9644655 0.90 TSHR (0.70) TSHRTP53ALDH1A1SMN1; SMN2SRD5A2
Benzoic Acid SCHEMBL1434863 0.90 TSHR (0.70) TSHRTP53ALDH1A1SMN1; SMN2SRD5A2
Benzoic Acid SCHEMBL4158962 0.90 TSHR (0.70) TSHRTP53ALDH1A1SMN1; SMN2SRD5A2
Terephthalic Acid SCHEMBL7845651 0.89 TSHR (0.52) TSHRTP53ALDH1A1SMN1; SMN2SRD5A2
Terephthalic Acid SCHEMBL4605471 0.89 TSHR (0.52) TSHRTP53ALDH1A1SMN1; SMN2SRD5A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 4455 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118878818-B Method for preparing regenerated polyesteramide based on ester-amide exchange reaction DONGHUA UNIVERSITY (CN) 2026-05-26 CN claimed
CN-122060109-A Hydrophobic heterogeneous polymerization ionic liquid catalyst and preparation method and application thereof 河北科技大学 2026-05-19 CN claimed
EP-4349881-B1 POLYESTER MATERIAL AND POLYESTER PRODUCT, AND PREPARATION METHODS THEREFOR AND USE THEREOF NINGBO INSTITUTE OF MATERIALS TECH & ENGINEERING CHINESE ACADEMY OF SCIENCES (CN) 2026-04-29 EP claimed
US-20260071932-A1 LIQUID DETECTION LAMINATES FOR CABLES AND METHODS FOR THE SAME NEENAH INC (US) 2026-03-12 US claimed
US-12552983-B2 Tracer compositions SAUDI ARABIAN OIL COMPANY (SA) 2026-02-17 US claimed
EP-3790930-B1 NOISE REDUCING FILLED POLYESTER SABIC GLOBAL TECHNOLOGIES BV (NL) 2025-08-27 EP claimed
US-12391826-B2 Noise reducing filled polyester SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2025-08-19 US claimed
US-20250237138-A1 TRACER COMPOSITIONS SAUDI ARABIAN OIL COMPANY (SA) 2025-07-24 US claimed
US-20250237137-A1 TRACER COMPOSITIONS SAUDI ARABIAN OIL COMPANY (SA) 2025-07-24 US claimed
US-20250236788-A1 TRACER COMPOSITIONS SAUDI ARABIAN OIL COMPANY (SA) 2025-07-24 US claimed
US-5117041-A Sulfonation process E. I. DU PONT DE NEMOURS AND COMPANY (US) 1992-05-26 US claimed
WO-1992006152-A1 POLYHYDROXY FATTY ACID AMIDES IN SOIL RELEASE AGENT-CONTAINING DETERGENT COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1992-04-16 WO claimed
EP-0287132-A2 Soil release polymer-coated substrate containing a laundry detergent THE PROCTER & GAMBLE COMPANY (US) 1988-10-19 EP claimed
CN-88100807-A That can improve scourability contains detergent for washing clothes and the substrate of the dirty polymkeric substance of the method that scribbles 1988-09-28 CN claimed
US-4770666-A Laundry composition containing peroxyacid bleach and soil release agent THE PROCTER & GAMBLE COMPANY (US) 1988-09-13 US claimed
EP-0271312-A2 Laundry composition containing peroxyacid bleach and soil release agent THE PROCTER & GAMBLE COMPANY (US) 1988-06-15 EP claimed
US-4740326-A Soil release polymer coated substrate containing a laundry detergent for improved cleaning performance THE PROCTER & GAMBLE COMPANY (US) 1988-04-26 US claimed
US-4304626-A FORMING THIN PROTECTIVE FILMS BY DISSOLVING THERMOPLASTIC PARTICLES COATED ON A PAPER BASE SHEET ALLIED PAPER INCORPORATED (US) 1981-12-08 US claimed
EP-0015146-A1 Polyester compositions and processes for moulding them ROHM AND HAAS COMPANY (US) 1980-09-03 EP claimed
US-4152511-A FIRE-RETARDANT MOLDING MATERIALS CONTAINING CHLORINE OR BROMINE DYNAMIT NOBEL AKTIENGESELLSCHAFT (DE) 1979-05-01 US claimed