Terephthalic Acid

Terephthalic Acid

SCHEMBL332989

C=CC=C.O=C(O)c1ccc(C(=O)O)cc1

nearest known ligand 0.71

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

OPRM1

The experimentally established mechanism targets of Terephthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.71
TP53 P04637 1/20 0.71
SRD5A2 P31213 4/20 0.60
CA1 P00915 2/20 0.57
CA2 P00918 2/20 0.57
CA12 O43570 1/20 0.57
CA3 P07451 1/20 0.57
TYR P14679 1/20 0.57
DRD1 P21728 1/20 0.57
CA4 P22748 1/20 0.57
CA6 P23280 1/20 0.57
CA5A P35218 1/20 0.57
CA7 P43166 1/20 0.57
CA9 Q16790 1/20 0.57
CA14 Q9ULX7 1/20 0.57
CA5B Q9Y2D0 1/20 0.57
ALDH1A1 P00352 3/20 0.56
DAO P14920 1/20 0.55
NAPRT Q6XQN6 1/20 0.55
ALOX15 P16050 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzoic Acid SCHEMBL997600 0.89 TSHR (0.74) TSHRTP53SRD5A2CA1CA2
Terephthalic Acid SCHEMBL787168 0.88 TSHR (0.71) TSHRTP53SRD5A2CA1CA2
Terephthalic Acid SCHEMBL540691 0.88 TSHR (0.71) TSHRTP53SRD5A2CA1CA2
Terephthalic Acid SCHEMBL31456604 0.86 TSHR (0.67) TSHRTP53SRD5A2CA1CA2
Terephthalic Acid SCHEMBL15050 0.86 TSHR (0.67) TSHRTP53SRD5A2CA1CA2
Terephthalic Acid SCHEMBL28737896 0.86 TSHR (0.67) TSHRTP53SRD5A2CA1CA2
Terephthalic Acid SCHEMBL8211964 0.86 TSHR (0.67) TSHRTP53SRD5A2CA1CA2
Terephthalic Acid SCHEMBL16470220 0.86 TSHR (0.67) TSHRTP53SRD5A2CA1CA2
Terephthalic Acid SCHEMBL9501513 0.86 TSHR (0.67) TSHRTP53SRD5A2CA1CA2
Terephthalic Acid SCHEMBL19025074 0.86 TSHR (0.67) TSHRTP53SRD5A2CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 602 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4299689-A2 COMPOSITIONS COMPRISING 1,2-DICHLORO-1,2-DIFLUOROETHYLENE FOR USE IN HEAT TRANSFER APPLICATIONS The Chemours Company FC, LLC (US) 2024-01-03 EP claimed
EP-3870667-B1 COMPOSITIONS CONTAINING DIFLUOROMETHANE, TETRAFLUOROPROPENE, AND CARBON DIOXIDE AND USES THEREOF CHEMOURS CO FC LLC (US) 2023-12-20 EP claimed
WO-2023232274-A1 METHOD FOR PRODUCING COMPOSITE FIBER MATERIALS WITH A PARTICULARLY LOW DEGREE OF FIBER WARPAGE BOND-LAMINATES GMBH (DE) 2023-12-07 WO claimed
EP-4173815-A1 ASYMMETRIC COMPOSITE MATERIAL ARRANGEMENT Bond Laminates GmbH (DE) 2023-05-03 EP claimed
US-11359123-B2 Compositions containing difluoromethane, tetrafluoropropene, and carbon dioxide and uses thereof THE CHEMOURS COMPANY FC, LLC (US) 2022-06-14 US claimed
US-11312891-B2 Refrigerant mixtures comprising difluoromethane, pentafluoroethane, tetrafluoroethane, tetrafluoropropene, and carbon dioxide and uses thereof THE CHEMOURS COMPANY FC, LLC (US) 2022-04-26 US claimed
CN-110343509-B Non-combustible mixed refrigerant capable of reducing greenhouse effect and application thereof 江西天宇化工有限公司 2021-09-14 CN claimed
US-20210179909-A1 COMPOSITIONS CONTAINING DIFLUOROMETHANE, TETRAFLUOROPROPENE, AND CARBON DIOXIDE AND USES THEREOF THE CHEMOURS COMPANY FC, LLC (US) 2021-06-17 US claimed
CN-112955520-A Compositions comprising difluoromethane, tetrafluoropropene, and carbon dioxide and uses thereof 科慕埃弗西有限公司 2021-06-11 CN claimed
US-20210066131-A1 THREE-DIMENSIONAL ELECTRONIC DEVICE THROUGH ORGANIC SOLVENT PLASTICIZATION PROCESS OF POLYMER FRAME, AND METHOD FOR MANUFACTURING SAME GWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2021-03-04 US claimed
EP-1478873-A2 THIN-WALLED LINER FOR HIGH-PRESSURE VESSELS Koldybaev, Sergei Glebovich (CZ) 2004-11-24 EP claimed
WO-2003069217-A2 THIN-WALLED LINER FOR HIGH-PRESSURE VESSELS KOLDYBAEV SERGEI GLEBOVICH (CZ) 2003-08-21 WO claimed
EP-1310142-A2 IMPROVED ADHESION OF POLYMERIC MATERIALS TO METAL SURFACES ATOTECH Deutschland GmbH (DE) 2003-05-14 EP claimed
WO-2002079542-A9 IMPROVED ADHESION OF POLYMERIC MATERIALS TO METAL SURFACES ATOTECH DEUTSCHLAND GMBH (DE) 2003-03-20 WO claimed
US-6506314-B1 Intergranular etching; immersing in plating solution con-taining hydrogen peroxide, sulfuric acid or a sulfonic acid, five membered nitrogen heterocyclic compound and such as triphenyl sulfonium chloride ATOTECH DEUTSCHLAND GMBH (DE) 2003-01-14 US claimed
WO-2002079542-A2 IMPROVED ADHESION OF POLYMERIC MATERIALS TO METAL SURFACES ATOTECH DEUTSCHLAND GMBH (DE) 2002-10-10 WO claimed
US-5928790-A IMPROVING ADHESION OF COPPER CIRCUITRY TO DIELECTRIC LAYER USING LAYER OF SPECIFIED METAL OXIDE AND/OR HYDROXIDE, ORGANOSILANE BONDING MIXTURE MCGEAN-ROHCO, INC. (US) 1999-07-27 US claimed
EP-0428887-B1 Process for producing a bonded ski SALOMON SA (FR) 1994-10-05 EP claimed
EP-0461453-B1 Method of bonding the components of a ski SALOMON SA (FR) 1994-08-17 EP claimed
EP-0264022-B1 COUPLING AGENT COMPOSITIONS FOR ADHERING THERMOPLASTIC RESINS TO INORGANIC SUBSTRATES DOW CORNING CORPORATION (US) 1993-03-03 EP claimed