Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | FABP6 | P51161 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Urea SCHEMBL6097799 | 0.93 | HSP90AA1 (0.33) | HSP90AA1FABP6 | |
| Bicarbonate SCHEMBL28192611 | 0.91 | FABP6 (0.32) | HSP90AA1FABP6 | |
| Acetamide SCHEMBL6098771 | 0.89 | LMNA (0.35) | HSP90AA1 | |
| Hydroxyamine SCHEMBL27914147 | 0.88 | — | — | |
| Acetamide SCHEMBL11140614 | 0.87 | HSP90AA1 (0.33) | HSP90AA1 | |
| Guanidine SCHEMBL7975804 | 0.86 | HSP90AA1 (0.32) | HSP90AA1FABP6 | |
| Acetic Acid SCHEMBL8308053 | 0.86 | HSP90AA1 (0.32) | HSP90AA1FABP6 | |
| Hydrazine SCHEMBL28115277 | 0.85 | — | — | |
| SCHEMBL4198 | 0.85 | — | — | |
| SCHEMBL80643 | 0.85 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6316405-B1 | CYCLOSPORIN A, POLYPEPTIDES, COMPONENT OF AMYLOID PLAQUES FOUND IN NEUROLOGICAL DISORDERS SUCH AS ALZHEIMER'S DISEASE, MULTIPLE SCLEROSIS, AND AMYOTROPHIC LATERAL SCLEROSIS. THE CONJUGATES ARE USEFUL IN THE TREATMENT OF NEUROLOGICAL | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2001-11-13 | — | — | US | disclosed |
| US-6270957-B1 | USEFUL IN THE TREATMENT AND PREVENTION OF HIV (HUMAN IMMUNODEFICIENCY VIRUS)-MEDIATED DISORDERS, INCLUDING AIDS (ACQUIRE IMMUNODEFICIENCY SYNDROME) | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2001-08-07 | — | — | US | disclosed |
| WO-1999010373-A1 | NON-IMMUNOSUPPRESSIVE CYCLOSPORINS AND THEIR USE IN THE PREVENTION AND TREATMENT OF HIV INFECTION | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 1999-03-04 | — | — | WO | disclosed |
| WO-1999010374-A1 | CYCLOSPORIN A CONJUGATES AND USES THEREFOR | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 1999-03-04 | — | — | WO | disclosed |