Known targets — ChEMBL curated mechanism
KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2
The experimentally established mechanism targets of Guanidine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Urea SCHEMBL6097799 | 0.88 | HSP90AA1 (0.33) | HSP90AA1FABP6 | |
| Hydroxyamine SCHEMBL27914147 | 0.88 | — | — | |
| Carbamic Acid SCHEMBL7871773 | 0.86 | HSP90AA1 (0.32) | HSP90AA1FABP6 | |
| Hydrazine SCHEMBL28115277 | 0.85 | — | — | |
| SCHEMBL4198 | 0.85 | — | — | |
| SCHEMBL969300 | 0.85 | — | — | |
| SCHEMBL80643 | 0.85 | — | — | |
| Fluoride SCHEMBL27461973 | 0.85 | — | — | |
| SCHEMBL4621927 | 0.85 | FABP6 (0.35) | HSP90AA1FABP6 | |
| Acetamide SCHEMBL6098771 | 0.84 | LMNA (0.35) | HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101094831-B | Make carbodiimide compound and the composition of substrates oil and water repellent | 3M INNOVATIVE PROPERTIES CO. (US) | 2015-11-25 | — | — | CN | disclosed |
| US-6297242-B1 | ACTIVE AGAINST METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS, VANCOMYCIN-RESISTANT ENTEROCOCCI AND PENICILLIN- AND CEPHALOSPORIN-RESISTANT STREPTOCOCCUS PNEUMONIAE. | ORTHO-MCNEIL PHARMACEUTICAL, INC. | 2001-10-02 | — | — | US | disclosed |
| US-6297242-B1 | ACTIVE AGAINST METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS, VANCOMYCIN-RESISTANT ENTEROCOCCI AND PENICILLIN- AND CEPHALOSPORIN-RESISTANT STREPTOCOCCUS PNEUMONIAE. | ORTHO-MCNEIL PHARMACEUTICAL, INC. | 2001-10-02 | — | — | US | disclosed |
| WO-2001042229-A1 | ANTIBACTERIAL AMIDINOMETHYL- AND GUANIDINOMETHYL-OXAZOLIDINONES | ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) | 2001-06-14 | — | — | WO | disclosed |