Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 12/20 | 0.60 |
| ▸ | SRC | P12931 | 4/20 | 0.45 |
| ▸ | PRKACA | P17612 | 3/20 | 0.45 |
| ▸ | PRKACG | P22612 | 3/20 | 0.45 |
| ▸ | PRKACB | P22694 | 3/20 | 0.45 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | MAP2 | P11137 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27948924 | 0.87 | GPR35 (0.66) | GPR35SRCPRKACAPRKACGPRKACB | |
| SCHEMBL9425166 | 0.79 | GPR35 (0.60) | GPR35SRCPRKACAPRKACGPRKACB | |
| SCHEMBL1155981 | 0.77 | NGFR (0.53) | MAP2 | |
| SCHEMBL11784003 | 0.77 | GPR35 (0.66) | GPR35SRCPRKACAPRKACGPRKACB | |
| SCHEMBL27442503 | 0.76 | MAP2 (0.59) | MAP2 | |
| SCHEMBL1156019 | 0.75 | CA1 (0.62) | — | |
| SCHEMBL14703001 | 0.75 | GPR35 (0.64) | GPR35SRCPRKACAPRKACGPRKACB | |
| SCHEMBL721793 | 0.74 | MAP2 (0.58) | MAP2 | |
| SCHEMBL31120728 | 0.71 | PRNP (0.61) | GPR35SRCPRKACAPRKACGPRKACB | |
| SCHEMBL1156584 | 0.71 | POLB (0.68) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6313313-B1 | WATER SOLUBLE CATIONIC AMIDE OR ESTER MADE FROM REACTION WITH 5,6-DIHYDROXYINDOLE-2-CARBOXYLIC ACID | BRISTOL-MYERS SQUIBB COMPANY | 2001-11-06 | — | — | US | disclosed |
| EP-0865269-A4 | SYNTHESIS OF QUATERNARY MELANIN COMPOUNDS AND THEIR USE AS HAIR DYES OR FOR SKIN TREATMENT | BRISTOL MYERS SQUIBB CO (US) | 2000-01-19 | — | — | EP | disclosed |
| US-5827330-A | OXIDATIVE POLYMERIZATION OF 5,6-DIHYDROXYINDOLE QUATERNARY AMINE DERIVATIVES | BRISTOL-MYERS SQUIBB CO. (US) | 1998-10-27 | — | — | US | disclosed |
| EP-0865269-A1 | SYNTHESIS OF QUATERNARY MELANIN COMPOUNDS AND THEIR USE AS HAIR DYES OR FOR SKIN TREATMENT | Bristol-Myers Squibb Company (US) | 1998-09-23 | — | — | EP | disclosed |
| US-5702712-A | Melanoquaternary compounds and their use as hair dyes and for skin treatment | CLAIROL, INCORPORATED (US) | 1997-12-30 | — | — | US | disclosed |
| US-5686084-A | Synthesis of quaternary melanin compounds and their use as hair dyes or for skin treatment | CLAIROL INCORPORATED (US) | 1997-11-11 | — | — | US | disclosed |
| WO-1997020542-A1 | SYNTHESIS OF QUATERNARY MELANIN COMPOUNDS AND THEIR USE AS HAIR DYES OR FOR SKIN TREATMENT | BRISTOL-MYERS SQUIBB COMPANY (US) | 1997-06-12 | — | — | WO | disclosed |