Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGXT | P21549 | 2/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16328950 | 0.82 | ALDH1A1 (0.50) | RECQLALDH1A1GAAIDO1LMNA | |
| SCHEMBL12337807 | 0.79 | RECQL (0.46) | RECQLALDH1A1GAAIDO1LMNA | |
| SCHEMBL17662330 | 0.78 | RECQL (0.45) | RECQLALDH1A1GAAIDO1LMNA | |
| SCHEMBL12085933 | 0.78 | RECQL (0.45) | RECQLALDH1A1GAAIDO1LMNA | |
| SCHEMBL9866115 | 0.78 | CYP1A2 (0.52) | RECQLALDH1A1GAAIDO1LMNA | |
| SCHEMBL915196 | 0.76 | IDO1 (0.54) | RECQLALDH1A1GAAIDO1LMNA | |
| SCHEMBL13870175 | 0.75 | RECQL (0.53) | RECQLALDH1A1GAAIDO1LMNA | |
| SCHEMBL22897410 | 0.75 | RECQL (0.58) | RECQLALDH1A1GAALMNAHTT | |
| SCHEMBL424945 | 0.74 | RECQL (0.51) | RECQLALDH1A1GAAIDO1LMNA | |
| SCHEMBL3053222 | 0.74 | ALDH1A1 (0.53) | RECQLALDH1A1GAAIDO1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7589170-B1 | Synthesis of cyclic peptides | THE UNIVERSITY OF QUEENSLAND (AU) | 2009-09-15 | — | — | US | disclosed |
| US-7589170-B1 | Synthesis of cyclic peptides | THE UNIVERSITY OF QUEENSLAND (AU) | 2009-09-15 | — | — | US | disclosed |
| US-6307018-B1 | TWO OLIGOPEPTIDES ARE LIGATED TO FORM A LIGATION PRODUCT HAVING AN AMINOTHIOESTER LINKAGE; IN A SECOND STEP, THE AMINOTHIOESTER LINKAGE REARRANGES TO FORM A PRODUCT HAVING AN N-SUBSTITUTED AMIDE LINKAGE | THE SCRIPPS RESEARCH INSTITUTE | 2001-10-23 | — | — | US | disclosed |
| WO-1998028434-A1 | GENERAL CHEMICAL LIGATION | THE SCRIPPS RESEARCH INSTITUTE (US) | 1998-07-02 | — | — | WO | disclosed |