Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.52 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.52 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | IDO1 | P14902 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | KIF11 | P52732 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11119737 | 0.86 | CYP2C19 (0.48) | CYP1A2RECQLIDO1CYP2D6CYP2C19 | |
| SCHEMBL915196 | 0.81 | IDO1 (0.54) | CYP1A2CYP2A6TAAR1RECQLALDH1A1 | |
| SCHEMBL13870175 | 0.80 | RECQL (0.53) | RECQLALDH1A1GAAIDO1LMNA | |
| SCHEMBL9214204 | 0.78 | CYP2D6 (0.55) | CYP1A2TAAR1ALDH1A1IDO1LMNA | |
| SCHEMBL424945 | 0.78 | RECQL (0.51) | RECQLALDH1A1GAAIDO1LMNA | |
| SCHEMBL11553154 | 0.78 | MEN1 (0.55) | CYP1A2TAAR1ALDH1A1IDO1LMNA | |
| SCHEMBL3053222 | 0.78 | ALDH1A1 (0.53) | RECQLALDH1A1GAAIDO1LMNA | |
| SCHEMBL672238 | 0.78 | TAAR1 (0.57) | TAAR1ALDH1A1IDO1KIF11CYP3A4 | |
| SCHEMBL7871845 | 0.78 | AGXT (0.50) | CYP1A2CYP2A6TAAR1RECQLALDH1A1 | |
| SCHEMBL10947999 | 0.78 | PRMT6 (0.57) | CYP1A2TAAR1ALDH1A1CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170115259-A1 | HIGH PERFORMANCE LIQUID CHROMATOGRAPHY METHOD FOR ANALYZING IMAGING AGENT, PRECURSOR OF IMAGING AGENT, OR INTERMEDIATE OF IMAGING AGENT | Institute of Nuclear Energy Research, Atomic Energy Council, Executive Yuan, R.O.C. (TW) | 2017-04-27 | — | — | US | disclosed |
| US-20130149249-A1 | IMAGING TUBERCULOSIS WITH PYRAZINAMIDE CONTRAST AGENTS | GE HEALTHCARE LIMITED (GB) | 2013-06-13 | — | — | US | disclosed |
| US-5021431-A | H-1 antagonist, h-2 agonist for treating hypertension, cardiac disease or arterial occlusion | HEUMANN PHARMA GMBH & CO. (DE) | 1991-06-04 | — | — | US | disclosed |
| EP-0199845-B1 | IMIDAZOLYLALKYLGUANIDIN DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | HEUMANN PHARMA GMBH & CO (DE) | 1990-08-01 | — | — | EP | disclosed |
| EP-0199845-A1 | Imidazolylalkylguanidin derivatives, process for their preparation and pharmaceutical compositions containing them | HEUMANN PHARMA GMBH & CO (DE) | 1986-11-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130149249-A1 | IMAGING TUBERCULOSIS WITH PYRAZINAMIDE CONTRAST AGENTS | CTPS1, CTPS2, MPI | CYP1A2 1428/4885CYP2A6 3485/4885TAAR1 1100/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.