Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.37 |
| ▸ | DGKA | P23743 | 2/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 4/20 | 0.35 |
| ▸ | CNR2 | P34972 | 2/20 | 0.34 |
| ▸ | NAAA | Q02083 | 1/20 | 0.34 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1104281 | 0.85 | FFAR4 (0.40) | KDM4EDUSP3MEN1KMT2ALMNA | |
| SCHEMBL441692 | 0.82 | KDM4E (0.64) | KDM4EDUSP3MEN1KMT2ALMNA | |
| SCHEMBL4567078 | 0.82 | ALDH1A1 (0.50) | LMNAHTR2CALDH1A1DGKAADRA2A | |
| SCHEMBL28591948 | 0.81 | KDM4E (0.67) | KDM4EDUSP3MEN1KMT2ALMNA | |
| SCHEMBL10061648 | 0.80 | ALDH1A1 (0.48) | KDM4EDUSP3MEN1KMT2ALMNA | |
| SCHEMBL16020427 | 0.80 | HTR2C (0.53) | LMNAHTR2CALDH1A1DGKAADRA2A | |
| SCHEMBL29171751 | 0.79 | HTR2C (0.44) | HTR2CALDH1A1DGKAADRA2AADRA1A | |
| SCHEMBL22028555 | 0.79 | HTR2C (0.46) | KDM4EDUSP3MEN1KMT2ALMNA | |
| SCHEMBL29110916 | 0.79 | FFAR4 (0.49) | KDM4EDUSP3MEN1KMT2ALMNA | |
| SCHEMBL1104267 | 0.79 | FFAR4 (0.49) | KDM4EDUSP3MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6326487-B1 | OLIGONUCLEOTIDES, ANTISENSE AGENTS, VIRICIDES AND GENE EXPRESSION | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2001-12-04 | — | — | US | disclosed |
| US-5696248-A | GENE EXPRESSION INHIBITOR, AS PROBES FOR DETECTING NUCLEIC ACIDS, AS VIRICIDES TREATING VIRAL DISEASE CAUSED BY HTLV, INFLUENZA, HEPATITIS VIRUS, PAPILLOMA VIRUS | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-12-09 | — | — | US | disclosed |