Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.64 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | DGKA | P23743 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.50 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.50 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.50 |
| ▸ | CNR2 | P34972 | 1/20 | 0.49 |
| ▸ | FAAH | O00519 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | PRKCA | P17252 | 1/20 | 0.49 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.49 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.49 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.49 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.49 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Alcohol SCHEMBL2356259 | 0.90 | DGKA (0.62) | KDM4EDUSP3MEN1KMT2ALMNA | |
| Glycerin SCHEMBL27302948 | 0.90 | KDM4E (0.73) | KDM4EDUSP3MEN1KMT2ALMNA | |
| Glycerin SCHEMBL27567967 | 0.90 | KDM4E (0.73) | KDM4EDUSP3MEN1KMT2ALMNA | |
| Glycerin SCHEMBL7523298 | 0.90 | KDM4E (0.73) | KDM4EDUSP3MEN1KMT2ALMNA | |
| SCHEMBL1004684 | 0.90 | KDM4E (0.68) | KDM4EDUSP3MEN1KMT2ALMNA | |
| Glycerin SCHEMBL7895803 | 0.90 | KDM4E (0.73) | KDM4EDUSP3MEN1KMT2ALMNA | |
| Cetyl Palmitate SCHEMBL28216712 | 0.90 | KDM4E (0.73) | KDM4EDUSP3MEN1KMT2ALMNA | |
| Glycerin SCHEMBL394035 | 0.90 | KDM4E (0.73) | KDM4EDUSP3MEN1KMT2ALMNA | |
| Glycerin SCHEMBL14562870 | 0.90 | KDM4E (0.73) | KDM4EDUSP3MEN1KMT2ALMNA | |
| SCHEMBL3487063 | 0.90 | DGKA (0.67) | KDM4EDUSP3MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160031781-A1 | AGENT FOR IMPROVING TISSUE PENETRATION | GENZYME CORPORATION (US) | 2016-02-04 | — | — | US | disclosed |
| US-20120064147-A1 | AGENT FOR IMPROVING TISSUE PENETRATION | GENZYME CORPORATION (US) | 2012-03-15 | — | — | US | disclosed |
| US-20090312440-A1 | AGENT FOR IMPROVING TISSUE PENETRATION | MAX-PLANCK-GESELLSCHAFT ZUR FOERDERUNG DER WISSENSHAFTEN E.V. (DE) | 2009-12-17 | — | — | US | disclosed |
| US-20040146535-A1 | Agent for improving tissue penetration | MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSHAFTEN E.V. (DE) | 2004-07-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040146535-A1 | Agent for improving tissue penetration | PGF, MMP8, MMP1 | KDM4E 4826/4885DUSP3 3728/4885MEN1 2672/4885 |
| US-20090312440-A1 | AGENT FOR IMPROVING TISSUE PENETRATION | PGF, MMP8, MMP1 | KDM4E 4826/4885DUSP3 3728/4885MEN1 2672/4885 |
| US-20160031781-A1 | AGENT FOR IMPROVING TISSUE PENETRATION | PGF, MMP8, MMP1 | KDM4E 4826/4885DUSP3 3728/4885MEN1 2672/4885 |
| US-20120064147-A1 | AGENT FOR IMPROVING TISSUE PENETRATION | PGF, MMP8, MMP1 | KDM4E 4826/4885DUSP3 3728/4885MEN1 2672/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.