Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL214198 | 0.87 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL215075 | 0.82 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL8028157 | 0.80 | PTGS2 (0.77) | PTGS2PTGS1 | |
| SCHEMBL5594618 | 0.80 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL7158835 | 0.80 | PTGS2 (0.95) | PTGS2PTGS1 | |
| SCHEMBL4213783 | 0.79 | PTGS2 (0.79) | PTGS2PTGS1 | |
| SCHEMBL5594124 | 0.79 | PTGS2 (1.00) | PTGS2PTGS1 | |
| Sulfamide SCHEMBL4639682 | 0.79 | PTGS2 (0.80) | PTGS2PTGS1 | |
| SCHEMBL5594526 | 0.78 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL5594259 | 0.78 | PTGS2 (1.00) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140181-A1 | COMBINATION THERAPY OF RADIATION AND A COX-2 INHIBITOR FOR THE TREATMENT OF NEOPLASIA | G.D. SEARLE & CO. (US) | 2001-10-10 | — | — | EP | claimed |
| JP-2001505564-A | — | — | 2001-04-24 | — | — | JP | claimed |
| WO-2000038716-A1 | COMBINATION THERAPY OF RADIATION AND A COX-2 INHIBITOR FOR THE TREATMENT OF NEOPLASIA | G.D. SEARLE & CO. (US) | 2000-07-06 | — | — | WO | claimed |
| EP-0941080-A2 | METHOD OF USING CYCLOOXYGENASE-2 INHIBITORS AS ANTI-ANGIOGENIC AGENTS | G.D. SEARLE & CO. (US) | 1999-09-15 | — | — | EP | claimed |
| WO-1998022101-A2 | METHOD OF USING CYCLOOXYGENASE-2 INHIBITORS AS ANTI-ANGIOGENIC AGENTS | G.D. SEARLE & CO. (US) | 1998-05-28 | — | — | WO | claimed |