Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22470611 | 1.00 | THRB (0.43) | THRBALDH1A1TSHR | |
| SCHEMBL194318 | 1.00 | THRB (0.43) | THRBALDH1A1TSHR | |
| SCHEMBL6225188 | 0.88 | THRB (0.35) | THRB | |
| SCHEMBL8968 | 0.84 | — | — | |
| SCHEMBL27028519 | 0.84 | THRB (0.55) | THRBALDH1A1TSHR | |
| SCHEMBL504018 | 0.84 | THRB (0.55) | THRBALDH1A1TSHR | |
| Water SCHEMBL3827178 | 0.78 | THRB (0.50) | THRBALDH1A1TSHR | |
| SCHEMBL402114 | 0.78 | THRB (0.50) | THRBALDH1A1TSHR | |
| SCHEMBL789340 | 0.78 | — | — | |
| SCHEMBL3230777 | 0.78 | THRB (0.50) | THRBALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 110 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115894463-A | Preparation method of ROCK inhibitor, intermediate thereof and preparation method of intermediate | 武汉朗来科技发展有限公司 | 2023-04-04 | — | — | CN | claimed |
| CN-114516779-B | Selective functionalization method of bicycloheptatriene-rubine (DHR) and derivatization application thereof | 中国科学院化学研究所 | 2023-03-31 | — | — | CN | claimed |
| CN-115413277-A | Solid forms of pyrazine-substituted nicotinamide, their preparation and use | 深圳市塔吉瑞生物医药有限公司 | 2022-11-29 | — | — | CN | claimed |
| CN-114853787-A | Near-infrared two-region AIE molecular probe and preparation method and application thereof | 河南大学 | 2022-08-05 | — | — | CN | claimed |
| CN-111087357-B | Preparation method of Prisamod | 中国医学科学院药物研究所 | 2022-07-19 | — | — | CN | claimed |
| CN-114685546-A | Hypochlorous acid fluorescence chemical sensor based on ICT and FRET mechanisms and synthetic method and application thereof | 青海师范大学 | 2022-07-01 | — | — | CN | claimed |
| CN-113717396-B | Copper (I) -based covalent metal organic framework material for catalyzing hydroboration reaction of alkyne and preparation method thereof | 暨南大学 | 2022-02-22 | — | — | CN | claimed |
| US-20260116903-A1 | AROMATIC HETEROCYCLIC COMPOUND, PHARMACEUTICAL COMPOSITION, AND USE THEREOF | RECURSION PHARMACEUTICALS INC (US) | 2026-04-30 | — | — | US | disclosed |
| US-12540149-B2 | Aromatic heterocyclic compound, pharmaceutical composition, and use thereof | RECURSION PHARMACEUTICALS, INC. (US) | 2026-02-03 | — | — | US | disclosed |
| WO-2025108411-A1 | EP300/CBP REGULATOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 北京沐华生物科技有限责任公司 | 2025-05-30 | — | — | WO | disclosed |
| WO-2025045233-A1 | MACROCYCLIC COMPOUNDS, PREPARATION METHOD THEREFOR, AND USE THEREOF | 劲方医药科技(上海)股份有限公司 | 2025-03-06 | — | — | WO | disclosed |
| CN-119522224-A | Preparation method and application of nitrogenous heterocyclic compound as ubiquitin-specific protease 1 inhibitor and application thereof | 上海济煜医药科技有限公司 | 2025-02-25 | — | — | CN | disclosed |
| WO-2025016323-A1 | PROTEIN ARGINASE METHYLTRANSFERASE-5 INHIBITOR AND MEDICAL USE THEREOF | 江苏亚虹医药科技股份有限公司 | 2025-01-23 | — | — | WO | disclosed |
| CN-108003140-A | Organic molecules particularly suitable for use in organic opto-electronic devices | 辛诺拉有限公司 | 2018-05-08 | — | — | CN | disclosed |
| US-9611222-B2 | Pyridine compounds and the uses thereof | PURDUE PHARMA L.P. (US) | 2017-04-04 | — | — | US | disclosed |
| US-20150259293-A1 | PYRIDINE COMPOUNDS AND THE USES THEREOF | PURDUE PHARMA L.P. | 2015-09-17 | — | — | US | disclosed |
| US-9056832-B2 | Pyridine compounds and the users thereof | PURDUE PHARMA L.P. (US) | 2015-06-16 | — | — | US | disclosed |
| US-20130303526-A1 | Pyridine Compounds and the Uses Thereof | PURDUE PHARMA L.P. (US) | 2013-11-14 | — | — | US | disclosed |
| EP-2616441-A2 | PYRIDINE COMPOUNDS AND THE USES THEREOF | Purdue Pharma LP (US) | 2013-07-24 | — | — | EP | disclosed |
| WO-2012035421-A2 | PYRIDINE COMPOUNDS AND THE USES THEREOF | PURDUE PHARMA L.P. (US) | 2012-03-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150259293-A1 | PYRIDINE COMPOUNDS AND THE USES THEREOF | TRPV1, CACNA1A, KCNA1 | THRB 2089/4885ALDH1A1 172/4885TSHR 1995/4885 |
| US-12540149-B2 | Aromatic heterocyclic compound, pharmaceutical composition, and use thereof | CDK7, CDK17, CDK1 | THRB 2317/4885ALDH1A1 4510/4885TSHR 3070/4885 |
| US-20260116903-A1 | AROMATIC HETEROCYCLIC COMPOUND, PHARMACEUTICAL COMPOSITION, AND USE THEREOF | CDK7, CDK8, CDK6 | THRB 1976/4885ALDH1A1 3407/4885TSHR 1386/4885 |
| US-20130303526-A1 | Pyridine Compounds and the Uses Thereof | TRPV1, CACNA1A, KCNA1 | THRB 2089/4885ALDH1A1 172/4885TSHR 1995/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.