Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 2/20 | 0.47 |
| ▸ | ANPEP | P15144 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | SDCBP | O00560 | 1/20 | 0.36 |
| ▸ | SDC2 | P34741 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | MME | P08473 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | PRCP | P42785 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7867488 | 0.86 | MME (0.43) | CYP1A2MMECYP2C19 | |
| SCHEMBL7872465 | 0.85 | MME (0.48) | TSHRCNR2CYP1A2MMECYP2C19 | |
| SCHEMBL7872426 | 0.85 | MME (0.48) | CTSKANPEPCNR2KDM4EMME | |
| SCHEMBL7860940 | 0.83 | HPGD (0.40) | ANPEPMAPK1MME | |
| SCHEMBL7867497 | 0.82 | CNR2 (0.45) | CNR2KDM4EMAPK1SMN1; SMN2 | |
| SCHEMBL7865912 | 0.78 | CYP1A2 (0.51) | CYP1A2MMECYP2C19 | |
| SCHEMBL7865908 | 0.77 | HTT (0.43) | CYP1A2MMECYP2C19 | |
| SCHEMBL7865403 | 0.75 | MME (0.47) | ANPEPCNR2MME | |
| SCHEMBL7865926 | 0.75 | KMT2A (0.48) | MMESMN1; SMN2 | |
| SCHEMBL9272404 | 0.73 | CTSK (0.43) | CTSKCYP1A2KDM4ESMN1; SMN2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1086107-A1 | ARTEMISININ DERIVATIVES, METHOD FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) | 2001-03-28 | — | — | EP | disclosed |
| WO-1999065914-A1 | ARTEMISININ DERIVATIVES, METHOD FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | SHANGHAI INSTITUTE OF MATERIA MEDICA (CN) | 1999-12-23 | — | — | WO | disclosed |