Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 4/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | CTSS | P25774 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CTSC | P53634 | 2/20 | 0.40 |
| ▸ | ACE | P12821 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7872404 | 0.86 | CTSK (0.47) | MMECYP1A2CYP2C19 | |
| SCHEMBL7872426 | 0.86 | MME (0.48) | MMECTSSALDH1A1 | |
| SCHEMBL7872465 | 0.86 | MME (0.48) | MMECYP1A2CYP2C19ALDH1A1 | |
| SCHEMBL7865912 | 0.84 | CYP1A2 (0.51) | MMECYP1A2CYP2C19 | |
| SCHEMBL7860940 | 0.84 | HPGD (0.40) | MMEL3MBTL1ALDH1A1 | |
| SCHEMBL7865403 | 0.84 | MME (0.47) | MME | |
| SCHEMBL7865926 | 0.84 | KMT2A (0.48) | MMEALDH1A1ACE | |
| SCHEMBL7867497 | 0.83 | CNR2 (0.45) | L3MBTL1MAPTALDH1A1 | |
| SCHEMBL11256931 | 0.82 | ALDH1A1 (0.54) | MAPTCTSSALDH1A1CTSC | |
| SCHEMBL7932238 | 0.82 | CTSS (0.42) | CTSSALDH1A1CTSC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1086107-A1 | ARTEMISININ DERIVATIVES, METHOD FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) | 2001-03-28 | — | — | EP | disclosed |
| WO-1999065914-A1 | ARTEMISININ DERIVATIVES, METHOD FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | SHANGHAI INSTITUTE OF MATERIA MEDICA (CN) | 1999-12-23 | — | — | WO | disclosed |