Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | TLR2 | O60603 | 11/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27598566 | 0.81 | TDP1 (0.45) | TSHREPHX2ALDH1A1GAATDP1 | |
| SCHEMBL3151254 | 0.81 | TDP1 (0.45) | TSHREPHX2ALDH1A1GAATDP1 | |
| SCHEMBL28281682 | 0.78 | TSHR (0.57) | TSHREPHX2ALDH1A1GAATDP1 | |
| SCHEMBL12629241 | 0.77 | TSHR (0.61) | TSHREPHX2ALDH1A1GAATDP1 | |
| SCHEMBL23031134 | 0.77 | TSHR (0.53) | TSHREPHX2ALDH1A1GAATDP1 | |
| SCHEMBL12664705 | 0.76 | TSHR (0.56) | TSHREPHX2ALDH1A1GAATDP1 | |
| SCHEMBL5899071 | 0.76 | TSHR (0.51) | TSHREPHX2ALDH1A1GAATDP1 | |
| SCHEMBL13991921 | 0.76 | TSHR (0.55) | TSHREPHX2ALDH1A1GAATDP1 | |
| SCHEMBL20529467 | 0.75 | CAPN1 (0.44) | EPHX2GAATDP1TLR2CYP2D6 | |
| SCHEMBL8693578 | 0.75 | DGKA (0.53) | EPHX2TLR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010116173-A1 | DEPSIPEPTIDES AND THEIR THERAPEUTIC USE | KARUS THERAPEUTICS LIMITED (GB) | 2010-10-14 | — | — | WO | disclosed |