Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.31 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5899043 | 0.83 | TSHR (0.47) | TSHRALDH1A1GAATDP1EPHX2 | |
| SCHEMBL12629241 | 0.77 | TSHR (0.61) | TSHRALDH1A1GAATDP1EPHX2 | |
| SCHEMBL1414996 | 0.76 | ALDH1A1 (0.47) | TSHRALDH1A1GAATDP1EPHX2 | |
| SCHEMBL28249376 | 0.76 | TSHR (0.70) | TSHRALDH1A1GAATDP1EPHX2 | |
| SCHEMBL5718452 | 0.76 | ALDH1A1 (0.47) | TSHRALDH1A1GAATDP1EPHX2 | |
| SCHEMBL27680065 | 0.76 | TSHR (0.46) | TSHRALDH1A1SMN1; SMN2FAAH | |
| SCHEMBL7872488 | 0.76 | TSHR (0.51) | TSHRALDH1A1GAATDP1EPHX2 | |
| SCHEMBL10606206 | 0.75 | TSHR (0.51) | TSHRALDH1A1GAATDP1EPHX2 | |
| SCHEMBL8100012 | 0.75 | TSHR (0.51) | TSHRALDH1A1GAATDP1EPHX2 | |
| SCHEMBL10501285 | 0.75 | TSHR (0.51) | TSHRALDH1A1GAATDP1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7045592-B2 | Processes for coupling amino acids using bis-(trichloromethyl) carbonate | DEVELOGEN ISRAEL LTD. (IL) | 2006-05-16 | — | — | US | disclosed |
| EP-1097164-A4 | PROCESSES FOR COUPLING AMINO ACIDS USING BIS-(TRICHLOROMETHYL) CARBONATE | PEPTOR LTD (IL) | 2005-05-25 | — | — | EP | disclosed |
| US-20030195331-A1 | Processes for coupling amino acids using bis-(trichloromethyl) carbonate | PEPTOR LTD. (IL) | 2003-10-16 | — | — | US | disclosed |
| US-6512092-B2 | Solid phase peptide synthesis; in situ generation of amino acid chloride by deblocking; coupling sterically hindered amino acid residues | PEPTOR LTD. (IL) | 2003-01-28 | — | — | US | disclosed |
| CN-1317011-A | Process for couping amino acids using bis-(trichloromethyl) carbonate | PEPTOR LTD (IL) | 2001-10-10 | — | — | CN | disclosed |
| US-20010007037-A1 | Processes for coupling amino acids using bis-(trichloromethyl) carbonate | FALB ELIEZER (IL) | 2001-07-05 | — | — | US | disclosed |
| EP-1097164-A1 | PROCESSES FOR COUPLING AMINO ACIDS USING BIS-(TRICHLOROMETHYL) CARBONATE | PEPTOR LTD (IL) | 2001-05-09 | — | — | EP | disclosed |
| WO-2000002898-A1 | PROCESSES FOR COUPLING AMINO ACIDS USING BIS-(TRICHLOROMETHYL) CARBONATE | PEPTOR LTD. (IL) | 2000-01-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010007037-A1 | Processes for coupling amino acids using bis-(trichloromethyl) carbonate | PTMS, BCAT1, DAO | TSHR 453/4885ALDH1A1 4814/4885GAA 2930/4885 |
| US-20030195331-A1 | Processes for coupling amino acids using bis-(trichloromethyl) carbonate | PTMS, BCAT1, DAO | TSHR 453/4885ALDH1A1 4814/4885GAA 2930/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.