Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK2 | Q9NRA0 | 9/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | SPHK1 | Q9NYA1 | 7/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | THRA | P10827 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RARB | P10826 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7872703 | 1.00 | SPHK2 (0.42) | SPHK2NPC1RAB9AKDM4ESMN1; SMN2 | |
| SCHEMBL10000265 | 0.90 | NPC1 (0.51) | NPC1RAB9AKDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL8390895 | 0.88 | TSHR (0.42) | SMN1; SMN2THRA | |
| SCHEMBL8390893 | 0.88 | TSHR (0.42) | SMN1; SMN2THRA | |
| SCHEMBL7877167 | 0.85 | NPC1 (0.51) | NPC1RAB9AKDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL9228238 | 0.85 | NPC1 (0.51) | NPC1RAB9AKDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL7878933 | 0.84 | NPC1 (0.50) | NPC1RAB9AKDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL10000263 | 0.84 | RAB9A (0.50) | NPC1RAB9AKDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL9154119 | 0.83 | RAB9A (0.37) | NPC1RAB9AKDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL9154571 | 0.83 | RAB9A (0.37) | NPC1RAB9AKDM4ESMN1; SMN2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0618914-B1 | OXIRANYL METHYL ETHERS EXHIBITING CHIRALITY, AND THEIR USE AS DOPANTS IN LIQUID-CRYSTAL MIXTURES | AVENTIS RES & TECH GMBH & CO (DE) | 2001-10-17 | — | — | EP | disclosed |
| US-5707545-A | OPTICAL APPARATUS FOR ELCTRONICS | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-01-13 | — | — | US | disclosed |