Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 5/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.38 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.38 |
| ▸ | PARL | Q9H300 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28811993 | 0.80 | KDM4E (0.40) | MAPTHTTRAB9AKMT2AALDH1A1 | |
| Acridine SCHEMBL7872845 | 0.79 | ALDH1A1 (0.46) | MAPTRAB9AKMT2AALDH1A1NPC1 | |
| SCHEMBL8643078 | 0.74 | MAPT (0.50) | MAPTHTTRAB9AKMT2AALDH1A1 | |
| SCHEMBL27729469 | 0.74 | ALDH1A1 (0.47) | MAPTHTTRAB9AKMT2AALDH1A1 | |
| SCHEMBL28897856 | 0.73 | ALDH1A1 (0.46) | MAPTHTTRAB9AKMT2AALDH1A1 | |
| SCHEMBL22721013 | 0.73 | KDM4E (0.49) | MAPTHTTRAB9AKMT2AALDH1A1 | |
| SCHEMBL9644825 | 0.73 | KMT2A (0.55) | MAPTHTTRAB9AKMT2AALDH1A1 | |
| SCHEMBL13978229 | 0.72 | ALDH1A1 (0.48) | MAPTHTTKMT2AALDH1A1KDM4E | |
| SCHEMBL13978014 | 0.72 | BCHE (0.41) | MAPTHTTKMT2AALDH1A1KDM4E | |
| SCHEMBL7780925 | 0.71 | MAPK1 (0.47) | MAPTKMT2AALDH1A1GLAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6316595-B1 | PNA synthesis using a base-labile amino protecting group | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2001-11-13 | — | — | US | disclosed |
| US-6121418-A | PNA synthesis using a base-labile amino protecting group | HOECHST AKTIENGESELLSCHAFT (DE) | 2000-09-19 | — | — | US | disclosed |
| US-6046306-A | SOLID PHASE SYNTHESIS OF PEPTIDE NUCLEIC ACIDS ALLOWING OLIGOMER TO BE CLEAVED OFF FROM THE SOLID SUPPORT UNDER THE ALKALINE CONDITIONS CONVENTIONALLY USED FOR OLIGONUCLEOTIDES | HOECHST AKTIENGESELLSCHAFT (DE) | 2000-04-04 | — | — | US | disclosed |