SCHEMBL7872878

SCHEMBL7872878

CC[O-].C[P+](C)(C)c1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 1/20 0.42
TP53 P04637 1/20 0.38
TAAR1 Q96RJ0 6/20 0.36
SIGMAR1 Q99720 3/20 0.36
SLC6A2 P23975 2/20 0.36
MAOA P21397 1/20 0.36
SLC6A4 P31645 1/20 0.36
SLC6A3 Q01959 1/20 0.36
LMNA P02545 1/20 0.36
CYP2A6 P11509 1/20 0.36
ADORA2A P29274 1/20 0.36
ADORA1 P30542 1/20 0.36
KCNN4 O15554 1/20 0.34
TRPA1 O75762 1/20 0.34
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
TSHR P16473 1/20 0.33
SLC18A2 Q05940 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7877206 0.86 HIF1A (0.41) HIF1ATAAR1SIGMAR1SLC6A2MAOA
SCHEMBL30596201 0.86 HIF1A (0.45) HIF1ATAAR1SIGMAR1SLC6A2MAOA
SCHEMBL7871206 0.84 HIF1A (0.42) HIF1ATP53TAAR1SIGMAR1SLC6A2
SCHEMBL7877207 0.84 HIF1A (0.42) HIF1ATP53TAAR1SIGMAR1SLC6A2
SCHEMBL9752186 0.83 HIF1A (0.43) HIF1ATAAR1SIGMAR1SLC6A2MAOA
Iodide SCHEMBL5087524 0.83 HIF1A (0.43) HIF1ATAAR1SIGMAR1SLC6A2MAOA
Water SCHEMBL1067231 0.83 HIF1A (0.43) HIF1ATAAR1SIGMAR1SLC6A2MAOA
Hydrochloric Acid SCHEMBL5085115 0.83 HIF1A (0.43) HIF1ATAAR1SIGMAR1SLC6A2MAOA
Fluoride Ion SCHEMBL1961963 0.83 HIF1A (0.43) HIF1ATAAR1SIGMAR1SLC6A2MAOA
Bromide SCHEMBL2355315 0.83 HIF1A (0.43) HIF1ATAAR1SIGMAR1SLC6A2MAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6316575-B1 MELT TRANSESTERIFICATION OF DIOL COMPOUND AND CARBOANTE COMPOUND USING CATALYST COMPRISING A PHOSPHORUS-CONTAINING BASIC COMPOUND QUATERNARY PHOSPHONIUM SALT TO FORM POLYCARBONATE IDEMITSU KOSAN CO., LTD. (JP) 2001-11-13 US claimed