SCHEMBL7877206

SCHEMBL7877206

C[O-].C[P+](C)(C)c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 2/20 0.41
TDP1 Q9NUW8 3/20 0.38
MAOA P21397 2/20 0.36
MAOB P27338 1/20 0.36
LMNA P02545 3/20 0.35
TSHR P16473 2/20 0.35
ALOX12 P18054 2/20 0.35
ACHE P22303 1/20 0.35
TAAR1 Q96RJ0 4/20 0.35
SLC6A2 P23975 2/20 0.35
SLC6A4 P31645 1/20 0.35
SLC6A3 Q01959 1/20 0.35
SIGMAR1 Q99720 1/20 0.35
CYP2A6 P11509 1/20 0.35
ADORA2A P29274 1/20 0.35
ADORA1 P30542 1/20 0.35
CYP3A4 P08684 2/20 0.33
ADRA2A P08913 1/20 0.33
ADRA2C P18825 1/20 0.33
CYP2D6 P10635 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30596201 0.94 HIF1A (0.45) HIF1ATDP1MAOALMNATSHR
SCHEMBL9752186 0.90 HIF1A (0.43) HIF1ATDP1MAOALMNATSHR
Fluoride Ion SCHEMBL1961963 0.90 HIF1A (0.43) HIF1ATDP1MAOALMNATSHR
Iodide SCHEMBL5087524 0.90 HIF1A (0.43) HIF1ATDP1MAOALMNATSHR
Bromide SCHEMBL2355315 0.90 HIF1A (0.43) HIF1ATDP1MAOALMNATSHR
Water SCHEMBL1067231 0.90 HIF1A (0.43) HIF1ATDP1MAOALMNATSHR
Hydrochloric Acid SCHEMBL5085115 0.90 HIF1A (0.43) HIF1ATDP1MAOALMNATSHR
SCHEMBL7872878 0.86 HIF1A (0.42) HIF1AMAOALMNATSHRTAAR1
Phenol SCHEMBL7874538 0.86 HIF1A (0.36) HIF1ATDP1MAOALMNATSHR
Sulfuric Acid SCHEMBL7643758 0.84 CA12 (0.36) HIF1ATDP1LMNATSHRKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6316575-B1 MELT TRANSESTERIFICATION OF DIOL COMPOUND AND CARBOANTE COMPOUND USING CATALYST COMPRISING A PHOSPHORUS-CONTAINING BASIC COMPOUND QUATERNARY PHOSPHONIUM SALT TO FORM POLYCARBONATE IDEMITSU KOSAN CO., LTD. (JP) 2001-11-13 US claimed