SCHEMBL7872908

SCHEMBL7872908

CCC(N=C=O)C1CCCC(N=C=O)C1

nearest known ligand 0.40

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9439963 0.88 ALDH1A1 (0.38) ALDH1A1
SCHEMBL16290175 0.87 SHBG (0.34)
SCHEMBL9439970 0.85 ALDH1A1 (0.36) ALDH1A1
SCHEMBL9440022 0.80 ALDH1A1 (0.41) ALDH1A1
SCHEMBL3416405 0.79 ALDH1A1 (0.44) ALDH1A1
SCHEMBL11013872 0.78 SHBG (0.45) ALDH1A1
SCHEMBL12488207 0.76 ALDH1A1 (0.48) ALDH1A1
SCHEMBL9418104 0.76 ALDH1A1 (0.48) ALDH1A1
SCHEMBL9439965 0.76 ALDH1A1 (0.38) ALDH1A1
SCHEMBL532565 0.75 SHBG (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0849268-B1 Polycyclic iminooxadiazindiones from (cyclo)aliphatic 1,4-diisocyanates BAYER AG (DE) 2001-10-10 EP disclosed
US-5882544-A Polycyclic iminooxadiazinediones from (cyclo)aliphatic 1,4-diisocyanates BAYER AKTIENGESELLSCHAFT (DE) 1999-03-16 US disclosed
EP-0849268-A1 Polycyclic iminooxadiazindiones from (cyclo)aliphatic 1,4-diisocyanates BAYER AG (DE) 1998-06-24 EP disclosed
US-5336749-A Alicyclic diamines, alicyclic diisocyanates and polyisocyanato-isocyanurates and method for the preparation thereof MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1994-08-09 US disclosed
EP-0394058-B1 ALICYCLIC DIAMINES, ALICYCLIC DIISOCYANATES AND POLYISOCYANATO-ISOCYANURATES AND METHOD FOR THE PREPARATION THEREOF MITSUI TOATSU CHEMICALS, Inc. (JP) 1993-08-25 EP disclosed
US-5210286-A Hydrogenation of corresponding aromatic compound, reaction with phosgene MITSUI TOATSU CHEMICALS, INC. (JP) 1993-05-11 US disclosed
US-5126426-A Catalytic hydrogenation of aromatic diamine MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1992-06-30 US disclosed
EP-0394058-A1 Alicyclic diamines, alicyclic diisocyanates and polyisocyanato-isocyanurates and method for the preparation thereof MITSUI TOATSU CHEMICALS, Inc. (JP) 1990-10-24 EP disclosed