SCHEMBL7873069

SCHEMBL7873069

O=[C]OCC(O)c1ccccc1[N+](=O)[O-]

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.47
CYP1A2 P05177 2/20 0.46
TSHR P16473 2/20 0.46
L3MBTL1 Q9Y468 1/20 0.40
NPC1 O15118 1/20 0.39
RECQL P46063 1/20 0.39
RAB9A P51151 1/20 0.39
HTT P42858 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
CYP3A4 P08684 1/20 0.38
CYP2D6 P10635 1/20 0.38
SLC6A2 P23975 1/20 0.38
SLC6A4 P31645 1/20 0.38
SLC6A3 Q01959 1/20 0.38
KCNH2 Q12809 1/20 0.38
HPGD P15428 1/20 0.37
PLAU P00749 1/20 0.37
GPR35 Q9HC97 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
KMT2A Q03164 3/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4797049 0.84 ALDH1A1 (0.47) ALDH1A1CYP1A2TSHRL3MBTL1NPC1
SCHEMBL21239 0.82 ALDH1A1 (0.47) ALDH1A1CYP1A2TSHRL3MBTL1NPC1
SCHEMBL30331074 0.79 CYP1A2 (0.54) ALDH1A1CYP1A2TSHRNPC1RECQL
SCHEMBL11461676 0.79 CYP1A2 (0.54) ALDH1A1CYP1A2TSHRNPC1RECQL
SCHEMBL7153686 0.77 CYP1A2 (0.53) ALDH1A1CYP1A2TSHRNPC1RECQL
SCHEMBL14599491 0.77 CYP1A2 (0.53) ALDH1A1CYP1A2TSHRNPC1RECQL
SCHEMBL267829 0.77 CYP1A2 (0.53) ALDH1A1CYP1A2TSHRNPC1RECQL
SCHEMBL12232402 0.77 CYP1A2 (0.53) ALDH1A1CYP1A2TSHRNPC1RECQL
SCHEMBL31145677 0.77 CYP1A2 (0.53) ALDH1A1CYP1A2TSHRNPC1RECQL
SCHEMBL11145783 0.77 CYP1A2 (0.47) ALDH1A1CYP1A2TSHRNPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6310083-B1 DERIVATIVES OF O-NITROMANDELYOXYCARBONYL WHICH ARE CAPABLE OF RELEASING AMINO ACIDS (OR DERIVATIVES THEREOF) UPON IRRADIATION WITH ULTRAVIOLET LIGHT; PRODUCING AMINO ACIDS (OR DERIVATIVES THEREOF) FOR USE IN NEUROPHYSIOLOGY STUDIES UNIVERSITY OF MARYLAND BOITECHNOLOGY INSTITUTE 2001-10-30 US disclosed
US-6043065-A Photosensitive organic compounds that release 2,5,-di(tert-butyl)hydroquinone upon illumination UNIVERSITY OF MARYLAND BIOTECHNOLOGY INSTITUTE (US) 2000-03-28 US disclosed