Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.66 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.66 |
| ▸ | CNR1 | P21554 | 4/20 | 0.66 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.66 |
| ▸ | LMNA | P02545 | 3/20 | 0.66 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.66 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.66 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.66 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.66 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.66 |
| ▸ | PGR | P06401 | 1/20 | 0.66 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.66 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.66 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.66 |
| ▸ | MAPT | P10636 | 1/20 | 0.66 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.66 |
| ▸ | ACAT1 | P24752 | 1/20 | 0.66 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11828154 | 0.93 | TSHR (0.55) | TSHRHIF1ACNR1MAPK1TDP1 | |
| SCHEMBL521541 | 0.86 | IDO1 (0.53) | TSHRHIF1ACNR1MAPK1TDP1 | |
| SCHEMBL29901560 | 0.86 | IDO1 (0.53) | TSHRHIF1ACNR1MAPK1TDP1 | |
| SCHEMBL28546831 | 0.83 | TSHR (0.47) | TSHRHIF1ACNR1MAPK1TDP1 | |
| SCHEMBL11639869 | 0.83 | TSHR (0.47) | TSHRHIF1ACNR1MAPK1TDP1 | |
| SCHEMBL11617245 | 0.81 | TSHR (0.50) | TSHRHIF1ACNR1MAPK1TDP1 | |
| Mitotane SCHEMBL4040 | 0.79 | TSHR (1.00) | TSHRHIF1ACNR1MAPK1TDP1 | |
| Mitotane SCHEMBL2352082 | 0.79 | TSHR (1.00) | TSHRHIF1ACNR1MAPK1TDP1 | |
| Mitotane SCHEMBL29360948 | 0.79 | TSHR (1.00) | TSHRHIF1ACNR1MAPK1TDP1 | |
| Mitotane SCHEMBL4041 | 0.79 | TSHR (1.00) | TSHRHIF1ACNR1MAPK1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-H2007-H1 | INSECTICIDES | FMC CORPORATION | 2001-12-04 | — | — | US | disclosed |
| WO-1997026252-A1 | INSECTICIDAL N-HETEROCYCLYLALKYL- OR N-[(POLYCYCLYL)-ALKYL]-N'-SUBSTITUTED PIPERAZINES | FMC CORPORATION (US) | 1997-07-24 | — | — | WO | disclosed |