Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 10/20 | 0.43 |
| ▸ | TMIGD3 | P0DMS9 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | XBP1 | P17861 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7869556 | 0.93 | ADORA3 (0.43) | MAPTKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL7876063 | 0.91 | ADORA3 (0.52) | MAPTKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL7864190 | 0.88 | ADORA3 (0.43) | MAPTKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL8136874 | 0.88 | ADORA3 (0.40) | ALDH1A1ADORA3TMIGD3TSHRHPGD | |
| SCHEMBL7872534 | 0.86 | ADORA3 (0.38) | MAPTADORA3TMIGD3TSHR | |
| SCHEMBL7873370 | 0.86 | ADORA3 (0.37) | ADORA3TMIGD3TSHR | |
| SCHEMBL7872512 | 0.86 | ADORA3 (0.38) | ADORA3TMIGD3TSHR | |
| SCHEMBL7871436 | 0.85 | TSHR (0.38) | ADORA3TMIGD3TSHR | |
| SCHEMBL7864225 | 0.82 | ADORA3 (0.41) | ADORA3TMIGD3TSHR | |
| SCHEMBL7872515 | 0.82 | ADORA3 (0.38) | MAPTADORA3TMIGD3TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6306853-B1 | DICARBOXYLIC ESTER DERIVATIVES OF DIHYDROPYRIDINE COMPOUNDS | NIKKEN CHEMICALS CO., LTD. (JP) | 2001-10-23 | — | — | US | disclosed |
| EP-1055672-A1 | 1,4-DIHYDROPYRIDINE DERIVATIVES | Nikken Chemicals Company, Limited (JP) | 2000-11-29 | — | — | EP | disclosed |