Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | MMP1 | P03956 | 4/20 | 0.33 |
| ▸ | MMP2 | P08253 | 3/20 | 0.33 |
| ▸ | MMP3 | P08254 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
| ▸ | BCHE | P06276 | 1/20 | 0.30 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
| ▸ | MMP8 | P22894 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11699853 | 0.77 | KDM4E (0.42) | MMP1MMP2MMP3USP2TSHR | |
| SCHEMBL14948795 | 0.76 | PPARD (0.52) | MEN1KMT2ARECQLMMP1MMP2 | |
| SCHEMBL779433 | 0.75 | TRPM8 (0.45) | — | |
| SCHEMBL9203527 | 0.75 | ANPEP (0.40) | MEN1KMT2ARECQLTSHRCA12 | |
| SCHEMBL3090613 | 0.75 | METAP1 (0.36) | — | |
| SCHEMBL4158403 | 0.74 | PPARD (0.39) | MMP1MMP2MMP3MMP8ALDH1A1 | |
| SCHEMBL1376856 | 0.73 | PPARD (0.52) | MMP1MMP2MMP3 | |
| SCHEMBL17782332 | 0.73 | THRB (0.36) | TSHR | |
| SCHEMBL13266984 | 0.73 | MEN1 (0.56) | MEN1KMT2AMMP1MMP2MMP3 | |
| SCHEMBL1251447 | 0.73 | PPARD (0.35) | MMP1MMP2MMP3MMP8CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012035303-A2 | A NOVEL PROCESS FOR SYNTHESIS OF RAMELTEON, AND KEY INTERMEDIATES FOR THE SYNTHESIS OF RAMELTEON | CIPLA LIMITED ET AL (IN) | 2012-03-22 | — | — | WO | disclosed |