Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 4/20 | 0.54 |
| ▸ | PDGFRA | P16234 | 4/20 | 0.54 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.51 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.47 |
| ▸ | BIRC5 | O15392 | 1/20 | 0.46 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.45 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.41 |
| ▸ | CSNK1G2 | P78368 | 1/20 | 0.41 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.41 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.41 |
| ▸ | MAP4K5 | Q9Y4K4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4014263 | 0.78 | CYP1A2 (0.43) | NISCHNPC1POLBRAB9ACYP1A2 | |
| SCHEMBL714449 | 0.77 | PDGFRB (0.53) | PDGFRBPDGFRACYP2A6NISCHBIRC5 | |
| SCHEMBL32667946 | 0.76 | PDGFRB (0.77) | PDGFRBPDGFRACYP2A6NISCHBIRC5 | |
| SCHEMBL2772360 | 0.76 | PDGFRB (0.77) | PDGFRBPDGFRACYP2A6NISCHBIRC5 | |
| SCHEMBL24412080 | 0.75 | PDGFRB (0.65) | PDGFRBPDGFRACYP2A6NISCHBIRC5 | |
| SCHEMBL6499308 | 0.75 | PDGFRB (0.51) | PDGFRBPDGFRACYP2A6NISCHBIRC5 | |
| SCHEMBL4279269 | 0.75 | PDGFRB (0.48) | PDGFRBPDGFRACYP2A6NISCHBIRC5 | |
| SCHEMBL1202054 | 0.73 | NOTUM (0.37) | CYP2A6NISCHNPC1POLBRAB9A | |
| SCHEMBL714450 | 0.73 | PDGFRB (0.66) | PDGFRBPDGFRACYP2A6NISCHBIRC5 | |
| SCHEMBL5579289 | 0.73 | NPC1 (0.78) | PDGFRBPDGFRACYP2A6NISCHBIRC5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6306853-B1 | DICARBOXYLIC ESTER DERIVATIVES OF DIHYDROPYRIDINE COMPOUNDS | NIKKEN CHEMICALS CO., LTD. (JP) | 2001-10-23 | — | — | US | claimed |