Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | METAP2 | P50579 | 1/20 | 0.52 |
| ▸ | METAP1 | P53582 | 1/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.52 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | CNR1 | P21554 | 3/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31669183 | 0.75 | KDM4E (0.54) | LMNAMETAP2METAP1HDAC6HSP90AA1 | |
| SCHEMBL3415803 | 0.74 | LMNA (0.71) | LMNAMETAP2METAP1HDAC6HSP90AA1 | |
| SCHEMBL28459061 | 0.72 | LMNA (0.69) | LMNAMETAP2METAP1HDAC6HSP90AA1 | |
| SCHEMBL11172201 | 0.72 | LMNA (0.50) | LMNAMETAP2METAP1HDAC6HSP90AA1 | |
| SCHEMBL15649670 | 0.71 | LMNA (0.47) | LMNAMETAP2METAP1HDAC6HSP90AA1 | |
| SCHEMBL7871674 | 0.71 | SMN1; SMN2 (0.82) | L3MBTL1NPSR1HTTKDM4EPOLB | |
| Carbamic Acid SCHEMBL28080599 | 0.71 | LMNA (0.68) | LMNAMETAP2METAP1HDAC6HSP90AA1 | |
| SCHEMBL3714420 | 0.70 | KDM4E (0.54) | LMNAMETAP2METAP1HDAC6HSP90AA1 | |
| SCHEMBL4555630 | 0.70 | KDM4E (0.46) | LMNAMETAP2METAP1HDAC6HSP90AA1 | |
| SCHEMBL111242 | 0.70 | LMNA (0.65) | LMNAMETAP2METAP1HDAC6HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6313315-B1 | RESOLUTION; ENANTIOMORPHIC PURIFICATION; CRYSTALLIZATION IN SOLVENT | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2001-11-06 | — | — | US | disclosed |
| EP-1057810-A1 | Method for producing n-protected-azetidine-2-carboxylic acids | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-12-06 | — | — | EP | disclosed |