Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Benzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.93 |
| ▸ | DAO | P14920 | 1/20 | 0.93 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.93 |
| ▸ | CES2 | O00748 | 3/20 | 0.74 |
| ▸ | CES1 | P23141 | 3/20 | 0.74 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.74 |
| ▸ | TP53 | P04637 | 1/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.56 |
| ▸ | CA12 | O43570 | 2/20 | 0.55 |
| ▸ | CA1 | P00915 | 2/20 | 0.55 |
| ▸ | CA2 | P00918 | 2/20 | 0.55 |
| ▸ | CA3 | P07451 | 2/20 | 0.55 |
| ▸ | CA4 | P22748 | 2/20 | 0.55 |
| ▸ | CA6 | P23280 | 2/20 | 0.55 |
| ▸ | CA5A | P35218 | 2/20 | 0.55 |
| ▸ | CA7 | P43166 | 2/20 | 0.55 |
| ▸ | CA9 | Q16790 | 2/20 | 0.55 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.55 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoic Acid SCHEMBL4591761 | 0.97 | TSHR (1.00) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL11602198 | 0.97 | TSHR (1.00) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL3966600 | 0.97 | TSHR (1.00) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL7719037 | 0.97 | TSHR (1.00) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL975929 | 0.97 | TSHR (1.00) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL407365 | 0.97 | TSHR (1.00) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL976149 | 0.97 | TSHR (1.00) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL149318 | 0.97 | TSHR (1.00) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL137419 | 0.97 | TSHR (1.00) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL1378 | 0.97 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4405523-A | PYROLYSIS OF YITRIUM, ERBIUM, DYSPROSOUM BENZOATES OR THE METAL OXIDE AND BENZOIC ACID | STANDARD OIL COMPANY (INDIANA) (US) | 1983-09-20 | — | — | US | claimed |
| EP-4423168-B1 | POLYETHER POLYMERIZATION PROCESS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2025-12-10 | — | — | EP | disclosed |
| US-12201971-B2 | Polyether polymerization process | DOW GLOBAL TECHNOLOGIES LLC (US) | 2025-01-21 | — | — | US | disclosed |
| US-20240392068-A1 | POLYETHER POLYMERIZATION PROCESS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2024-11-28 | — | — | US | disclosed |
| EP-4423168-A1 | POLYETHER POLYMERIZATION PROCESS | Dow Global Technologies LLC (US) | 2024-09-04 | — | — | EP | disclosed |
| CN-118043376-A | Polyether polymerization process | 陶氏环球技术有限责任公司 | 2024-05-14 | — | — | CN | disclosed |
| US-20230356207-A1 | Polyether Polymerization Process | DOW GLOBAL TECHNOLOGIES LLC | 2023-11-09 | — | — | US | disclosed |
| US-11745174-B2 | Polyether polymerization process | DOW GLOBAL TECHNOLOGIES LLC (US) | 2023-09-05 | — | — | US | disclosed |
| WO-2023075987-A1 | POLYETHER POLYMERIZATION PROCESS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2023-05-04 | — | — | WO | disclosed |
| CN-110832007-B | Polyether polymerization process | 陶氏环球技术有限责任公司 | 2023-04-04 | — | — | CN | disclosed |
| CN-103403061-A | Alkylene oxide polymerization using a double metal cyanide catalyst complex and a magnesium, group 3-group 15 metal or lanthanide series metal compound | DOW GLOBAL TECHNOLOGIES INC | 2013-11-20 | — | — | CN | disclosed |
| EP-2658895-A1 | ALKYLENE OXIDE POLYMERIZATION USING A DOUBLE METAL CYANIDE CATALYST COMPLEX AND A MAGNESIUM, GROUP 3-GROUP 15 METAL OR LANTHANIDE SERIES METAL COMPOUND | Dow Global Technologies LLC (US) | 2013-11-06 | — | — | EP | disclosed |
| US-20130289236-A1 | ALKYLENE OXIDE POLYMERIZATION USING A DOUBLE METAL CYANIDE CATALYST COMPLEX AND A MAGNESIUM, GROUP 3 - GROUP 15 METAL OR LANTHANIDE SERIES METAL COMPOUND | DOW BENELUX B.V. (NL) | 2013-10-31 | — | — | US | disclosed |
| WO-2013095976-A2 | PROCESS FOR MAKING HYBRID POLYESTER-POLYETHER POLYOLS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2013-06-27 | — | — | WO | disclosed |
| WO-2012091968-A1 | ALKYLENE OXIDE POLYMERIZATION USING A DOUBLE METAL CYANIDE CATALYST COMPLEX AND A MAGNESIUM, GROUP 3-GROUP 15 METAL OR LANTHANIDE SERIES METAL COMPOUND | DOW GLOBAL TECHNOLOGIES LLC (US) | 2012-07-05 | — | — | WO | disclosed |
| CN-101723659-B | Method for preparing superconductive layer of coated conductor by organic deposition of low-fluorine metal | NW INST NON FERROUS METAL RES | 2012-04-25 | — | — | CN | disclosed |
| CN-101723659-A | Method for preparing superconductive layer of coated conductor by organic deposition of low-fluorine metal | NW INST NON FERROUS METAL RES | 2010-06-09 | — | — | CN | disclosed |
| US-6326459-B1 | METATHESIS | RHODIA CHIMIE (FR) | 2001-12-04 | — | — | US | disclosed |
| CN-1278746-A | Composition based o a grafted metal oxide, preparation and use in a polymerisation method by opening oxygenated cycles | RHODIA CHIMIE SA (FR) | 2001-01-03 | — | — | CN | disclosed |
| US-4405523-A | PYROLYSIS OF YITRIUM, ERBIUM, DYSPROSOUM BENZOATES OR THE METAL OXIDE AND BENZOIC ACID | STANDARD OIL COMPANY (INDIANA) (US) | 1983-09-20 | — | — | US | disclosed |