Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | TOP1 | P11387 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | APAF1 | O14727 | 1/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7869894 | 0.92 | NR3C1 (0.50) | NR3C1RAB9AMEN1KMT2ATOP1 | |
| SCHEMBL12104260 | 0.75 | TOP1 (0.48) | RAB9AMEN1KMT2ATOP1ALDH1A1 | |
| SCHEMBL7873111 | 0.74 | NR3C1 (0.55) | NR3C1RAB9AMEN1KMT2ATOP1 | |
| SCHEMBL1133437 | 0.73 | APP (0.55) | MEN1KMT2ATOP1ALDH1A1MAPT | |
| SCHEMBL5461155 | 0.73 | ALDH1A1 (0.50) | RAB9AMEN1KMT2ATOP1ALDH1A1 | |
| SCHEMBL10177310 | 0.72 | ALDH1A1 (0.43) | RAB9AMEN1KMT2ATOP1ALDH1A1 | |
| SCHEMBL548076 | 0.72 | CA1 (0.52) | RAB9AMEN1KMT2ATOP1ALDH1A1 | |
| SCHEMBL7873621 | 0.71 | NR3C1 (0.49) | NR3C1RAB9AMEN1KMT2ATOP1 | |
| Hydrochloric Acid SCHEMBL7196666 | 0.71 | NR3C1 (0.49) | NR3C1RAB9AMEN1KMT2ATOP1 | |
| SCHEMBL7945498 | 0.71 | NR3C1 (0.49) | NR3C1RAB9AMEN1KMT2ATOP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6313242-B1 | PROVIDING A METALLOCENE CATALYST AND CONTACTING WITH AN ETHYLENICALLY UNSATURATED MONOMER WHICH CONTAINS THREE OR MORE CARBON ATOMS OR IS A SUBSTITUTED VINYL COMPOUND IN PRESENCE OF ORGANOALUMINUM COCATALYST TO PRODUCE ISOSPECIFIC POLYMER | FINA TECHNOLOGY, INC. | 2001-11-06 | — | — | US | disclosed |
| US-5945365-A | Stereorigid bis-fluorenyl metallocenes | FINA TECHNOLOGY, INC. (US) | 1999-08-31 | — | — | US | disclosed |