Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.39 |
| ▸ | MAP3K9 | P80192 | 1/20 | 0.38 |
| ▸ | MAP3K11 | Q16584 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | CA6 | P23280 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | NPC1 | O15118 | 4/20 | 0.34 |
| ▸ | RAB9A | P51151 | 4/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8857148 | 0.85 | PNMT (0.43) | PNMTMAP3K9MAP3K11PGRMAOA | |
| SCHEMBL29859431 | 0.85 | PNMT (0.43) | PNMTMAP3K9MAP3K11PGRMAOA | |
| SCHEMBL13777275 | 0.82 | PNMT (0.39) | PNMTMAP3K9MAP3K11PGRMAOA | |
| SCHEMBL9841135 | 0.80 | PGR (0.40) | PNMTMAP3K9MAP3K11PGRMAOA | |
| Hydrochloric Acid SCHEMBL9579948 | 0.79 | MAP3K9 (0.41) | PNMTMAP3K9MAP3K11PGRMAOA | |
| SCHEMBL5404542 | 0.79 | MAP3K9 (0.41) | PNMTMAP3K9MAP3K11PGRMAOA | |
| SCHEMBL7141052 | 0.79 | PNMT (0.39) | PNMTMAP3K9MAP3K11PGRMAOA | |
| SCHEMBL5404545 | 0.79 | PNMT (0.42) | PNMTMAP3K9MAP3K11PGRMAOA | |
| SCHEMBL7873112 | 0.78 | MAPT (0.48) | CA1CA2CA4CA6ADORA2A | |
| Hydrochloric Acid SCHEMBL7251521 | 0.77 | MAP3K9 (0.41) | PNMTMAP3K9MAP3K11PGRMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6313242-B1 | PROVIDING A METALLOCENE CATALYST AND CONTACTING WITH AN ETHYLENICALLY UNSATURATED MONOMER WHICH CONTAINS THREE OR MORE CARBON ATOMS OR IS A SUBSTITUTED VINYL COMPOUND IN PRESENCE OF ORGANOALUMINUM COCATALYST TO PRODUCE ISOSPECIFIC POLYMER | FINA TECHNOLOGY, INC. | 2001-11-06 | — | — | US | disclosed |
| US-5945365-A | Stereorigid bis-fluorenyl metallocenes | FINA TECHNOLOGY, INC. (US) | 1999-08-31 | — | — | US | disclosed |