Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA5 | P31644 | 16/20 | 0.54 |
| ▸ | ITGA5 | P08648 | 2/20 | 0.46 |
| ▸ | NTRK1 | P04629 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2628078 | 1.00 | GABRA5 (0.54) | GABRA5ITGA5NTRK1 | |
| SCHEMBL298033 | 1.00 | GABRA5 (0.54) | GABRA5ITGA5NTRK1 | |
| SCHEMBL296603 | 0.93 | GABRA5 (0.62) | GABRA5ITGA5 | |
| SCHEMBL296088 | 0.87 | GABRA5 (0.53) | GABRA5NTRK1 | |
| SCHEMBL2628079 | 0.87 | GABRA5 (0.53) | GABRA5NTRK1 | |
| SCHEMBL296703 | 0.85 | GABRA5 (0.60) | GABRA5ITGA5 | |
| SCHEMBL2628069 | 0.85 | GABRA5 (0.59) | GABRA5ITGA5 | |
| SCHEMBL286341 | 0.85 | GABRA5 (0.59) | GABRA5ITGA5 | |
| SCHEMBL7870299 | 0.85 | GABRA5 (0.59) | GABRA5ITGA5 | |
| SCHEMBL297966 | 0.85 | GABRA5 (0.59) | GABRA5ITGA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127975-A1 | ISOXAZOLE-PYRAZOLE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2010-11-11 | — | — | WO | disclosed |