Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2628069 | 1.00 | GABRA5 (0.59) | GABRA5ITGA5 | |
| SCHEMBL286341 | 1.00 | GABRA5 (0.59) | GABRA5ITGA5 | |
| SCHEMBL286300 | 0.93 | GABRA5 (0.67) | GABRA5ITGA5 | |
| SCHEMBL286174 | 0.86 | GABRA5 (0.67) | GABRA5ITGA5 | |
| SCHEMBL298033 | 0.85 | GABRA5 (0.54) | GABRA5ITGA5 | |
| SCHEMBL2628078 | 0.85 | GABRA5 (0.54) | GABRA5ITGA5 | |
| SCHEMBL7873697 | 0.85 | GABRA5 (0.54) | GABRA5ITGA5 | |
| SCHEMBL286424 | 0.85 | GABRA5 (0.64) | GABRA5ITGA5 | |
| SCHEMBL286658 | 0.84 | GABRA5 (0.59) | GABRA5 | |
| SCHEMBL286301 | 0.84 | GABRA5 (0.54) | GABRA5ITGA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127975-A1 | ISOXAZOLE-PYRAZOLE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2010-11-11 | — | — | WO | disclosed |