Sugi Predict

Sugi Predict / Compounds / SCHEMBL787382

SCHEMBL787382

SCHEMBL787382

c1ccc(-c2cccc3c2oc2c(-c4ccc5c(c4)[nH]c4ccccc45)cccc23)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ AHR P35869 1/20 0.44
▸ SMN1; SMN2 Q16637 3/20 0.44
▸ HPGD P15428 1/20 0.44
▸ MAPK1 P28482 1/20 0.44
▸ HTT P42858 1/20 0.44
▸ ALOX5 P09917 1/20 0.43
▸ KIF11 P52732 7/20 0.43
▸ ALDH1A1 P00352 4/20 0.41
▸ HSD17B10 Q99714 2/20 0.41
▸ MAPT P10636 1/20 0.41
▸ GPR3 P46089 1/20 0.41
▸ BRD4 O60885 2/20 0.40
▸ BRD2 P25440 2/20 0.40
▸ BRD3 Q15059 2/20 0.40
▸ PRKDC P78527 3/20 0.39
▸ CDK4 P11802 1/20 0.38
▸ CCND1 P24385 1/20 0.38
▸ PIK3CD O00329 2/20 0.38
▸ PIK3CA P42336 2/20 0.38
▸ PIK3CB P42338 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10226461 0.97 ALOX5 (0.46) AHRSMN1; SMN2HPGDMAPK1HTT
SCHEMBL788287 0.91 AHR (0.44) AHRSMN1; SMN2HPGDMAPK1HTT
SCHEMBL788435 0.90 AHR (0.43) AHRSMN1; SMN2HPGDMAPK1HTT
SCHEMBL786991 0.88 ALOX5 (0.46) AHRSMN1; SMN2HPGDMAPK1HTT
SCHEMBL787146 0.87 AHR (0.41) AHRSMN1; SMN2HPGDMAPK1HTT
SCHEMBL787216 0.87 ALOX5 (0.59) AHRALOX5KIF11ALDH1A1HSD17B10
SCHEMBL30959748 0.87 ALOX5 (0.59) AHRALOX5KIF11ALDH1A1HSD17B10
SCHEMBL22289310 0.87 ALOX5 (0.59) AHRALOX5KIF11ALDH1A1HSD17B10
SCHEMBL26055682 0.87 ALOX5 (0.47) AHRSMN1; SMN2HPGDMAPK1HTT
SCHEMBL787222 0.87 ALOX5 (0.44) AHRSMN1; SMN2HPGDMAPK1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020032447-A1 ORGANIC ELECTRONIC ELEMENT COMPRISING, AS HOST MATERIAL, MIXTURE OF DIFFERENT KINDS OF COMPOUNDS, AND ELECTRONIC DEVICE THEREOF 덕산네오룩스 주식회사 2020-02-13 — — WO disclosed
WO-2020032424-A1 ORGANIC ELECTRONIC ELEMENT COMPRISING, AS HOST MATERIAL, MIXTURE OF DIFFERENT KINDS OF COMPOUNDS, AND ELECTRONIC DEVICE THEREOF 덕산네오룩스 주식회사 2020-02-13 — — WO disclosed
US-9450188-B2 Carbazole derivative, light-emitting element material and organic semiconductor material SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2016-09-20 — — US disclosed
US-20140145175-A1 Carbazole Derivative, Light-Emitting Element Material and Organic Semiconductor Material SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-05-29 — — US disclosed
US-8642782-B2 Carbazole derivative, light-emitting element material and organic semiconductor material SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-02-04 — — US disclosed
US-20120071668-A1 Carbazole Derivative, Light-Emitting Element Material and Organic Semiconductor Material SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-03-22 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120071668-A1 Carbazole Derivative, Light-Emitting Element Material and Organic Semiconductor Material SLC39A3, SULT1A1, NUTF2 AHR 71/4885SMN1; SMN2 3933/4885HPGD 1834/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.