Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 6/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.61 |
| ▸ | USP2 | O75604 | 2/20 | 0.56 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | HTT | P42858 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13444686 | 0.88 | ALDH1A1 (0.56) | PTPN1LMNAL3MBTL1TDP1MAPK1 | |
| SCHEMBL13444685 | 0.87 | L3MBTL1 (0.64) | LMNAL3MBTL1TDP1MAPK1USP2 | |
| SCHEMBL2010417 | 0.85 | USP2 (0.67) | PTPN1LMNAL3MBTL1MAPK1USP2 | |
| SCHEMBL13444680 | 0.84 | L3MBTL1 (0.60) | LMNAL3MBTL1TDP1MAPK1USP2 | |
| SCHEMBL14327977 | 0.84 | L3MBTL1 (0.64) | LMNAL3MBTL1TDP1MAPK1USP2 | |
| SCHEMBL7030629 | 0.83 | PTPN1 (0.60) | PTPN1LMNAL3MBTL1MAPK1USP2 | |
| SCHEMBL5285484 | 0.83 | L3MBTL1 (0.59) | LMNAL3MBTL1TDP1MAPK1USP2 | |
| SCHEMBL30717645 | 0.83 | USP2 (0.61) | PTPN1LMNAL3MBTL1MAPK1USP2 | |
| SCHEMBL11825493 | 0.82 | GLA (0.68) | PTPN1LMNAL3MBTL1MAPK1USP2 | |
| SCHEMBL27397039 | 0.81 | KDM4E (0.56) | LMNAL3MBTL1MAPK1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6329502-B1 | VIRICIDES AGAINST HUMAN IMMUNODEFICIENCY VIRUS; TREATMENT OF AIDS (ACQUIRED IMMUNE DEFICIENCY SYNDROME) | JAPAN ENERGY CORPORATION (JP) | 2001-12-11 | — | — | US | disclosed |
| US-6313094-B1 | COMPOSITION FOR INHIBITING HUMAN IMMUNODEFICIENCY VIRUS REPLICATION | JAPAN ENERGY CORPORATION (JP) | 2001-11-06 | — | — | US | disclosed |