Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | MITF | O75030 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | CDC42 | P60953 | 3/20 | 0.33 |
| ▸ | RAC1 | P63000 | 3/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17361251 | 0.84 | CDC42 (0.46) | ALDH1A1KDM4EMAPTGAAL3MBTL1 | |
| SCHEMBL7875841 | 0.84 | CDC42 (0.46) | ALDH1A1KDM4EMAPTGAAL3MBTL1 | |
| SCHEMBL27977488 | 0.75 | — | — | |
| SCHEMBL9458684 | 0.74 | CDC42 (0.40) | ALDH1A1KDM4EMAPTGAAL3MBTL1 | |
| SCHEMBL9383103 | 0.74 | KDM4E (0.40) | ALDH1A1KDM4E | |
| SCHEMBL9381071 | 0.74 | CA12 (0.36) | ALDH1A1KDM4EMAPTTP53 | |
| SCHEMBL11201877 | 0.74 | CDC42 (0.41) | ALDH1A1KDM4EMAPTGAAL3MBTL1 | |
| SCHEMBL10641885 | 0.73 | OPRM1 (0.36) | ALDH1A1KDM4EMAPTGAANPC1 | |
| SCHEMBL11197597 | 0.72 | CDC42 (0.40) | ALDH1A1KDM4EMAPTGAAL3MBTL1 | |
| SCHEMBL11443496 | 0.72 | CHRM2 (0.41) | ALDH1A1KDM4EL3MBTL1TP53LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111788204-B | Substituted pyrrolizine compounds as inhibitors of HBV replication | 吉利德科学公司 | 2023-05-05 | — | — | CN | disclosed |
| US-6323344-B1 | HYDROLYZING 5-BENZOYL-2,3-DIHYDRO-1H-PYRROLIZINE-1-CARBOXAMIDES COMPOUND IN PRESENCE OF STRONG BASE TO FORM KETOROLAC | SYNTEX (U.S.A.) INC. | 2001-11-27 | — | — | US | disclosed |
| US-6197976-B1 | ACYLATION, SALT FORMATION, DEAMINATION | SYNTEX (U.S.A.) LLC | 2001-03-06 | — | — | US | disclosed |