SCHEMBL7873904

SCHEMBL7873904

C=C(C)C(=O)OC(CO)(OCC)OC(=O)C(=C)C

nearest known ligand 0.40

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.40
ALDH1A1 P00352 2/20 0.37
TSHR P16473 3/20 0.35
KDM4E B2RXH2 1/20 0.31
PKM P14618 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL268177 0.96 THRB (0.40) THRBALDH1A1TSHRKDM4EPKM
SCHEMBL1779169 0.86 THRB (0.41) THRBALDH1A1TSHR
SCHEMBL27603259 0.83 THRB (0.39) THRBALDH1A1TSHR
SCHEMBL20135806 0.81 THRB (0.46) THRBALDH1A1TSHR
SCHEMBL269871 0.81 ALDH1A1 (0.39) THRBALDH1A1TSHR
SCHEMBL28762304 0.80 THRB (0.38) THRB
SCHEMBL2784716 0.78 THRB (0.38) THRBALDH1A1TSHR
SCHEMBL28436042 0.78 THRB (0.44) THRBALDH1A1TSHR
SCHEMBL269870 0.78 THRB (0.42) THRBALDH1A1TSHR
SCHEMBL1494476 0.77 ALDH1A1 (0.44) THRBALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6323360-B1 USED IN THE PREPARATION OF A STAR-SHAPED OR BRANCHED OR GEL POLY METHYL METHACRYLATE THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK 2001-11-27 US disclosed