Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 6/20 | 0.77 |
| ▸ | HTR2B | P41595 | 3/20 | 0.77 |
| ▸ | USP2 | O75604 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.58 |
| ▸ | CTSC | P53634 | 1/20 | 0.57 |
| ▸ | MC4R | P32245 | 2/20 | 0.56 |
| ▸ | GID4 | Q8IVV7 | 1/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.53 |
| ▸ | HTR2A | P28223 | 1/20 | 0.51 |
| ▸ | DPP4 | P27487 | 1/20 | 0.50 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1789145 | 1.00 | HTR2C (0.77) | HTR2CHTR2BUSP2ALDH1A1HPGD | |
| SCHEMBL5154669 | 1.00 | HTR2C (0.77) | HTR2CHTR2BUSP2ALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL7607289 | 0.98 | HTR2C (0.75) | HTR2CHTR2BUSP2ALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL18337901 | 0.98 | HTR2C (0.75) | HTR2CHTR2BUSP2ALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL4368425 | 0.98 | HTR2C (0.75) | HTR2CHTR2BUSP2ALDH1A1HPGD | |
| SCHEMBL9469301 | 0.95 | HTR2C (0.71) | HTR2CHTR2BUSP2ALDH1A1HPGD | |
| SCHEMBL9469302 | 0.95 | HTR2C (0.71) | HTR2CHTR2BUSP2ALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL18337653 | 0.94 | HTR2C (0.70) | HTR2CHTR2BUSP2ALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL3267987 | 0.94 | HTR2C (0.70) | HTR2CHTR2BUSP2ALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL18337654 | 0.94 | HTR2C (0.70) | HTR2CHTR2BUSP2ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0758342-B1 | NEW PEPTIDE ACTIVE SUBSTANCE AND PRODUCTION THEREOF | BASF AG (DE) | 2000-01-05 | — | — | EP | claimed |
| US-5864012-A | OLIGOPEPTIDES AS ANTITUMOR AGENTS | BASF AKTIENGESELLSCHAFT (DE) | 1999-01-26 | — | — | US | claimed |
| EP-3334710-B1 | COMPOSITIONS AND METHODS FOR TREATING AND PREVENTING NEURODEGENERATIVE DISORDERS | ALZHEON INC (US) | 2023-10-04 | — | — | EP | disclosed |
| US-10759765-B2 | Heterocyclic carboxylic acid amide ligand and applications thereof in copper catalyzed coupling reaction of aryl halogeno substitute | CE PHARM CO., LTD. (CN) | 2020-09-01 | — | — | US | disclosed |
| US-20190127337-A1 | HETEROCYCLIC CARBOXYLIC ACID AMIDE LIGAND AND APPLICATIONS THEREOF IN COPPER CATALYZED COUPLING REACTION OF ARYL HALOGENO SUBSTITUTE | CE PHARM CO., LTD. (CN) | 2019-05-02 | — | — | US | disclosed |
| EP-3444031-A1 | HETEROCYCLIC CARBOXYLIC ACID AMIDE LIGAND AND APPLICATIONS THEREOF IN COPPER CATALYZED COUPLING REACTION OF ARYL HALOGENO SUBSTITUTE | Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences (CN) | 2019-02-20 | — | — | EP | disclosed |
| WO-2017177979-A1 | HETEROCYCLIC CARBOXYLIC ACID AMIDE LIGAND AND APPLICATIONS THEREOF IN COPPER CATALYZED COUPLING REACTION OF ARYL HALOGENO SUBSTITUTE | 中国科学院上海有机化学研究所 | 2017-10-19 | — | — | WO | disclosed |
| US-8048862-B2 | Macrocyclic inhibitors of hepatitis C virus replication | INTERMUNE, INC. (US) | 2011-11-01 | — | — | US | disclosed |
| US-8048862-B2 | Macrocyclic inhibitors of hepatitis C virus replication | INTERMUNE, INC. (US) | 2011-11-01 | — | — | US | disclosed |
| US-20110059047-A1 | NOVEL MACROCYCLIC INHIBITORS OF HEPATITIS C VIRUS REPLICATION | INTERMUNE, INC. (US) | 2011-03-10 | — | — | US | disclosed |
| US-20090269305-A1 | NOVEL MACROCYCLIC INHIBITORS OF HEPATITIS C VIRUS REPLICATION | INTERMUNE, INC. (US) | 2009-10-29 | — | — | US | disclosed |
| US-20090269305-A1 | NOVEL MACROCYCLIC INHIBITORS OF HEPATITIS C VIRUS REPLICATION | INTERMUNE, INC. (US) | 2009-10-29 | — | — | US | disclosed |
| US-5965700-A | Preparation of active peptides | BASF AKTIENGESELLSCHAFT (DE) | 1999-10-12 | — | — | US | disclosed |
| US-5864012-A | OLIGOPEPTIDES AS ANTITUMOR AGENTS | BASF AKTIENGESELLSCHAFT (DE) | 1999-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090269305-A1 | NOVEL MACROCYCLIC INHIBITORS OF HEPATITIS C VIRUS REPLICATION | EIF2AK2, HAVCR2, ZC3HAV1 | HTR2C 3859/4885HTR2B 4587/4885USP2 2540/4885 |
| US-20110059047-A1 | NOVEL MACROCYCLIC INHIBITORS OF HEPATITIS C VIRUS REPLICATION | EIF2AK2, HAVCR2, ZC3HAV1 | HTR2C 3859/4885HTR2B 4587/4885USP2 2540/4885 |
| US-20190127337-A1 | HETEROCYCLIC CARBOXYLIC ACID AMIDE LIGAND AND APPLICATIONS THEREOF IN COPPER CATALYZED COUPLING REACTION OF ARYL HALOGENO SUBSTITUTE | AOC1, AOC2, AOC3 | HTR2C 1937/4885HTR2B 3092/4885USP2 1174/4885 |
| US-10759765-B2 | Heterocyclic carboxylic acid amide ligand and applications thereof in copper catalyzed coupling reaction of aryl halogeno substitute | AOC1, AOC2, AOC3 | HTR2C 1937/4885HTR2B 3092/4885USP2 1174/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.