Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 5/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.34 |
| ▸ | ADRA1B | P35368 | 4/20 | 0.34 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | TBXAS1 | P24557 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7083166 | 0.81 | ADRA1A (0.40) | TSHRADRA1AADRA1BADRA1DHRH1 | |
| SCHEMBL7083169 | 0.81 | ADRA1A (0.40) | TSHRADRA1AADRA1BADRA1DHRH1 | |
| SCHEMBL7075810 | 0.81 | ADRA1A (0.40) | TSHRADRA1AADRA1BADRA1DHRH1 | |
| SCHEMBL7972617 | 0.76 | ADRA1A (0.39) | ADRA1AADRA1BADRA1DHRH1KDM4E | |
| SCHEMBL8186925 | 0.74 | HTR2B (0.34) | ADRA1AADRA1BADRA1DHRH1TBXAS1 | |
| SCHEMBL7865187 | 0.74 | GRM5 (0.42) | CYP19A1CYP11B1CYP11B2ALDH1A1KDM4E | |
| SCHEMBL6959819 | 0.72 | ADRA1A (0.52) | TSHRADRA1AADRA1BADRA1DHRH1 | |
| SCHEMBL6082094 | 0.72 | ADRA1A (0.52) | TSHRADRA1AADRA1BADRA1DHRH1 | |
| SCHEMBL7095750 | 0.72 | ADRA1A (0.52) | TSHRADRA1AADRA1BADRA1DHRH1 | |
| SCHEMBL6961064 | 0.69 | ADRA1A (0.41) | TSHRADRA1AADRA1BADRA1DHRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6319932-B1 | USEFUL FOR TREATING BENIGN PROSTATIC HYPERPLASIA | MERCK & CO., INC. | 2001-11-20 | — | — | US | disclosed |