SCHEMBL7874320

SCHEMBL7874320

c1ccc2c(-c3ccsc3)cccc2c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NQO2 P16083 1/20 0.53
CYP2A6 P11509 2/20 0.48
CYP2B6 P20813 2/20 0.48
CYP2E1 P05181 1/20 0.48
GPR84 Q9NQS5 1/20 0.47
MAOB P27338 1/20 0.46
ENPP1 P22413 2/20 0.43
TMIGD3 P0DMS9 1/20 0.43
ADORA2A P29274 1/20 0.43
ADORA1 P30542 1/20 0.43
CA12 O43570 3/20 0.42
CA1 P00915 3/20 0.42
CA2 P00918 3/20 0.42
CA9 Q16790 3/20 0.42
PTPRC P08575 1/20 0.42
PDGFRB P09619 1/20 0.42
PDGFRA P16234 1/20 0.42
HDAC8 Q9BY41 1/20 0.41
HDAC6 Q9UBN7 1/20 0.41
CYP3A4 P08684 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31378184 1.00 NQO2 (0.53) NQO2CYP2A6CYP2B6CYP2E1GPR84
SCHEMBL26259994 0.89 CYP2A6 (0.52) NQO2CYP2A6CYP2B6CYP2E1GPR84
SCHEMBL14461163 0.87 NQO2 (0.53) NQO2CYP2A6CYP2B6CYP2E1GPR84
SCHEMBL28724812 0.86 NQO2 (0.56) NQO2CYP2A6CYP2B6CYP2E1GPR84
SCHEMBL26259978 0.85 CYP2A6 (0.58) NQO2CYP2A6CYP2B6CYP2E1GPR84
SCHEMBL26089210 0.82 PTPRC (0.45) NQO2CYP2A6CYP2B6CYP2E1GPR84
SCHEMBL30366970 0.81 TNF (0.47) NQO2CYP2A6CYP2B6CYP2E1ENPP1
SCHEMBL4946960 0.80 CYP2A6 (0.64) NQO2CYP2A6CYP2B6CYP2E1GPR84
SCHEMBL11771248 0.80 NQO2 (0.53) NQO2CYP2A6CYP2B6CYP2E1GPR84
SCHEMBL26260013 0.79 CYP2A6 (0.46) NQO2CYP2A6CYP2B6CYP2E1GPR84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119101046-B 3-Naphthyl thiophene derivative, and preparation method and application thereof SHENYANG PHARMACEUTICAL UNIVERSITY (CN) 2026-05-26 CN claimed
CN-119101046-A 3-Naphthyl thiophene derivative, and preparation method and application thereof 沈阳药科大学 2024-12-10 CN claimed
US-20230287262-A1 PHOTON UPCONVERSION COMPOSITION, FILM, METHOD FOR CONVERTING VISIBLE LIGHT INTO ULTRAVIOLET LIGHT, AND COMPOUND KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2023-09-14 US disclosed
CN-105255480-B A kind of diazosulfide luminescent material of oxygen containing diphenylphosphine and preparation and application 华南理工大学 2017-10-20 CN disclosed
CN-105255480-A Diazosulfide light-emitting material containing diphenyl phosphine oxide and preparation method and application thereof UNIV SOUTH CHINA TECH 2016-01-20 CN disclosed
EP-0261837-B1 Process for the preparation of electrically conductive material SANYO ELECTRIC CO (JP) 2001-07-11 EP disclosed
EP-0350166-B1 Polymer compositions NIPPON OIL CO LTD (JP) 1994-03-23 EP disclosed
US-5120472-A POLYMER COMPOSITIONS NIPPON OIL COMPANY (JP) 1992-06-09 US disclosed
EP-0350166-A2 Polymer compositions NIPPON OIL CO., LTD. (JP) 1990-01-10 EP disclosed
US-4795687-A POLYTHIENYLENE, POLYPRYRROLE OR POLYANILINE MATERIAL PREPARED BY OXIDATION POLYMERIZATION MITSUBISHI KASEI CORP. (JP) 1989-01-03 US disclosed
EP-0261837-A2 Electrically conductive material and a process for the preparation of same and secondary battery using the electrically conductive material Sanyo Electric Co., Ltd (JP) 1988-03-30 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230287262-A1 PHOTON UPCONVERSION COMPOSITION, FILM, METHOD FOR CONVERTING VISIBLE LIGHT INTO ULTRAVIOLET LIGHT, AND COMPOUND NUDC, CCNL2, SPIN3 NQO2 3653/4885CYP2A6 807/4885CYP2B6 516/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.