SCHEMBL7874413

SCHEMBL7874413

Cc1cc(C#N)[c]c(C#N)c1

nearest known ligand 0.36

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.36
CYP2A6 P11509 1/20 0.36
TSHR P16473 2/20 0.33
THRB P10828 1/20 0.31
ACHE P22303 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL510533 0.87 ALDH1A1 (0.32) ALDH1A1CYP2A6
SCHEMBL3337149 0.84 ALDH1A1 (0.33) ALDH1A1CYP2A6ACHE
SCHEMBL457229 0.80
SCHEMBL11503690 0.80 ACHE (0.35) ACHE
SCHEMBL2093167 0.74 TSHR (0.41) ALDH1A1CYP2A6TSHR
SCHEMBL9176392 0.74 TSHR (0.39) ALDH1A1TSHR
SCHEMBL9179301 0.72 MEN1 (0.32)
SCHEMBL350245 0.70
Acetonitrile SCHEMBL25293727 0.68 ALDH1A1 (0.50) ALDH1A1CYP2A6TSHRTHRBACHE
SCHEMBL3712582 0.67 TSHR (0.32) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5420254-A Monoazo dyes for textiles such as cellulose or polyesters SANDOZ LTD. (CH) 1995-05-30 US claimed
CN-101273095-A Disperse azo dyes and mixtures comprising these disperse azo dyes CLARIANT INT LTD (VG) 2008-09-24 CN disclosed
EP-0261837-B1 Process for the preparation of electrically conductive material SANYO ELECTRIC CO (JP) 2001-07-11 EP disclosed
US-5420254-A Monoazo dyes for textiles such as cellulose or polyesters SANDOZ LTD. (CH) 1995-05-30 US disclosed
US-4795687-A POLYTHIENYLENE, POLYPRYRROLE OR POLYANILINE MATERIAL PREPARED BY OXIDATION POLYMERIZATION MITSUBISHI KASEI CORP. (JP) 1989-01-03 US disclosed
EP-0261837-A2 Electrically conductive material and a process for the preparation of same and secondary battery using the electrically conductive material Sanyo Electric Co., Ltd (JP) 1988-03-30 EP disclosed