SCHEMBL7874449

SCHEMBL7874449

Nc1cc(N)c(O)c(S(=O)(=O)c2ccccc2)c1

nearest known ligand 0.56

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 5/20 0.56
HKDC1 Q2TB90 1/20 0.54
GAA P10253 2/20 0.50
POLB P06746 1/20 0.50
GFER P55789 1/20 0.50
ALDH1A1 P00352 4/20 0.47
KDM4E B2RXH2 2/20 0.47
PKM P14618 1/20 0.47
HPGD P15428 1/20 0.47
LMNA P02545 1/20 0.41
CASP1 P29466 1/20 0.41
CASP7 P55210 1/20 0.41
HSD17B10 Q99714 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
NPSR1 Q6W5P4 1/20 0.40
TSHR P16473 1/20 0.40
HTT P42858 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13406869 0.83 HTR6 (0.53) HTR6HKDC1GAAPOLBGFER
SCHEMBL4464881 0.81 HTR6 (0.55) HTR6HKDC1GAAPOLBGFER
SCHEMBL565003 0.80 HTR6 (0.69) HTR6HKDC1GAAPOLBGFER
SCHEMBL17774551 0.79 POLB (0.69) HTR6HKDC1GAAPOLBGFER
SCHEMBL29712886 0.78 HTR6 (0.66) HTR6HKDC1GAAPOLBGFER
SCHEMBL1162839 0.78 HTR6 (0.66) HTR6HKDC1GAAPOLBGFER
SCHEMBL9070302 0.78 HTR6 (0.66) HTR6HKDC1GAAPOLBGFER
SCHEMBL29480329 0.78 HTR6 (0.66) HTR6HKDC1GAAPOLBGFER
SCHEMBL8066769 0.77 HTR6 (0.58) HTR6HKDC1GAAPOLBGFER
SCHEMBL8723742 0.77 POLB (0.67) HTR6HKDC1GAAPOLBGFER

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6319656-B1 FORMING FILM OF A NEGATIVE-WORKING PHOTO-SENSITIVE POLYIMIDE PRECURSOR ON A SUBSTRATE; EXPOSING FILM TO LIGHT THROUGH A MASK HAVING A PREDETERMINED PATTERN; DEVELOPING THE EXPOSED FILM USING AN ALKALINE AQUEOUS SOLUTION HITACHI CHEMICAL COMPANY, LTD. (JP) 2001-11-20 US disclosed