Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 6/20 | 0.69 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | ACLY | P53396 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | CA6 | P23280 | 1/20 | 0.44 |
| ▸ | CA5A | P35218 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL564728 | 0.86 | GAA (0.60) | HTR6GAATSHRACLYMMP2 | |
| SCHEMBL12903976 | 0.86 | HTR6 (0.57) | HTR6GAAPOLBGFERALDH1A1 | |
| SCHEMBL395274 | 0.82 | HTR6 (1.00) | HTR6GAAPOLBGFERALDH1A1 | |
| SCHEMBL30751995 | 0.82 | HTR6 (1.00) | HTR6GAAPOLBGFERALDH1A1 | |
| SCHEMBL139251 | 0.81 | POLB (0.55) | HTR6GAAPOLBGFERALDH1A1 | |
| SCHEMBL15444 | 0.81 | HTR6 (0.74) | HTR6GAAPOLBGFERALDH1A1 | |
| SCHEMBL8852806 | 0.80 | HTR6 (0.56) | HTR6GAAPOLBGFERALDH1A1 | |
| SCHEMBL7874449 | 0.80 | HTR6 (0.56) | HTR6GAAPOLBGFERALDH1A1 | |
| SCHEMBL11576082 | 0.79 | HTR6 (0.71) | HTR6GAAPOLBGFERALDH1A1 | |
| SCHEMBL10425221 | 0.78 | HSD11B1 (0.53) | HTR6GAAPOLBGFERTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8674029-B2 | Method of preparing stabilized polymeric systems using polymeric peroxides | Sunocs LLC (US) | 2014-03-18 | — | — | US | disclosed |
| EP-1697354-B1 | ISOTHIAZOLE DIOXIDES AS CXC- AND CC- CHEMOKINE RECEPTOR LIGANDS | MERCK SHARP & DOHME (US) | 2013-08-07 | — | — | EP | disclosed |
| EP-1539678-B1 | 3,4-DI-SUBSTITUTED CYCLOBUTENE-1, 2-DIONES AS CXC-CHEMOKINE RECEPTOR LIGANDS | MERCK SHARP & DOHME (US) | 2012-09-05 | — | — | EP | disclosed |
| US-20120035307-A1 | PROCESS FOR MAKING STABLIZED POLYMERIC SYSTEMS WITH NANOSTRUCTURES | SONG CHENGQIAN (US) | 2012-02-09 | — | — | US | disclosed |
| US-20120035315-A1 | METHOD OF PREPARING STABLIZED POLYMERIC SYSTEMS USING POLYMERIC PEROXIDES | SONG CHENGQIAN (US) | 2012-02-09 | — | — | US | disclosed |
| US-20110213029-A1 | 3,4-Di-Substituted Cyclobutene-1,2-Diones as CXC-Chemokine Receptor Ligands | SCHERING CORPORATION (US) | 2011-09-01 | — | — | US | disclosed |
| US-20110213029-A1 | 3,4-Di-Substituted Cyclobutene-1,2-Diones as CXC-Chemokine Receptor Ligands | SCHERING CORPORATION (US) | 2011-09-01 | — | — | US | disclosed |
| US-7964646-B2 | 3,4-DI-substituted cyclobutene-1,2-diones as CXC-chemokine receptor ligands | SCHERING CORPORATION (US) | 2011-06-21 | — | — | US | disclosed |
| US-7964646-B2 | 3,4-DI-substituted cyclobutene-1,2-diones as CXC-chemokine receptor ligands | SCHERING CORPORATION (US) | 2011-06-21 | — | — | US | disclosed |
| US-7786149-B2 | Thiadiazoles as CXC- and CC- chemokine receptor ligands | SCHERING CORP. (US) | 2010-08-31 | — | — | US | disclosed |
| US-20060208227-A1 | Antioxidant and bisaminophenol derivative | IDEMITSU LOSAN CO., LTD (JP) | 2006-09-21 | — | — | US | disclosed |
| US-20060135733-A1 | Polycarbonate - ultem block copolymers | GENERAL ELECTRIC COMPANY (US) | 2006-06-22 | — | — | US | disclosed |
| WO-2006066055-A2 | POLYCARBONATE-ULTEM BLOCK COPOLYMERS | GENERAL ELECTRIC COMPANY (US) | 2006-06-22 | — | — | WO | disclosed |
| EP-1612254-A1 | ANTIOXIDANT AND BISAMINOPHENOL DERIVATIVE | IDEMITSU KOSAN COMPANY LIMITED (JP) | 2006-01-04 | — | — | EP | disclosed |
| EP-0217301-B1 | POLY(ETHERIMIDE-CARBONATE)BLOCK COPOLYMERS AND POLYMER BLENDS CONTAINING SAME | GENERAL ELECTRIC COMPANY (US) | 1991-08-07 | — | — | EP | disclosed |
| EP-0217302-B1 | HYDROXY TERMINATED POLYETHERIMIDE OLIGOMERS | GENERAL ELECTRIC COMPANY (US) | 1990-11-14 | — | — | EP | disclosed |
| US-4657977-A | MOLDING MATERIALS | GENERAL ELECTRIC COMPANY (US) | 1987-04-14 | — | — | US | disclosed |
| EP-0217302-A1 | Hydroxy terminated polyetherimide oligomers | GENERAL ELECTRIC COMPANY (US) | 1987-04-08 | — | — | EP | disclosed |
| EP-0217301-A1 | Poly(etherimide-carbonate)block copolymers and polymer blends containing same | GENERAL ELECTRIC COMPANY (US) | 1987-04-08 | — | — | EP | disclosed |
| US-4611048-A | Hydroxy terminated polyetherimide oligomers | GENERAL ELECTRIC COMPANY (US) | 1986-09-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110213029-A1 | 3,4-Di-Substituted Cyclobutene-1,2-Diones as CXC-Chemokine Receptor Ligands | CCR1, ACKR3, CXCR1 | HTR6 3295/4885GAA 4850/4885POLB 2094/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.