Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.36 |
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | GAA | P10253 | 4/20 | 0.35 |
| ▸ | HPGD | P15428 | 4/20 | 0.35 |
| ▸ | GLA | P06280 | 2/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7867798 | 0.87 | GAA (0.40) | P2RX7KDM4EALDH1A1MAPTGAA | |
| SCHEMBL28479062 | 0.77 | HSP90AA1 (0.38) | KDM4EALDH1A1MAPTGAAHPGD | |
| SCHEMBL2153609 | 0.76 | TSHR (0.47) | KDM4EALDH1A1MAPTHPGDGLA | |
| SCHEMBL7635960 | 0.75 | SRD5A2 (0.41) | KDM4EALDH1A1POLBKMT2ASMN1; SMN2 | |
| SCHEMBL17622544 | 0.74 | AURKA (0.36) | P2RX7KDM4EALDH1A1 | |
| SCHEMBL8769047 | 0.74 | ALDH1A1 (0.44) | KDM4EALDH1A1MAPTGAAPOLB | |
| SCHEMBL7639805 | 0.73 | KMT2A (0.55) | ALDH1A1MAPTGAAPOLBKMT2A | |
| SCHEMBL7528356 | 0.73 | MAPK14 (0.45) | ALDH1A1MAPTGAAKMT2ASMN1; SMN2 | |
| SCHEMBL1585342 | 0.71 | GAA (0.37) | KDM4EALDH1A1MAPTGAAHPGD | |
| SCHEMBL1198771 | 0.70 | SMN1; SMN2 (0.41) | KDM4EALDH1A1MAPTGAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6316595-B1 | PNA synthesis using a base-labile amino protecting group | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2001-11-13 | — | — | US | disclosed |