Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | EP300 | Q09472 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.34 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.34 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18649675 | 0.81 | EP300 (0.55) | ALDH1A1KDM4EPOLBEP300KMT2A | |
| SCHEMBL3357453 | 0.81 | ALDH1A1 (0.45) | ALDH1A1MAPTKDM4EPOLBEP300 | |
| SCHEMBL27707200 | 0.81 | EP300 (0.42) | EP300 | |
| SCHEMBL11718699 | 0.79 | EP300 (0.43) | ALDH1A1KDM4EEP300LMNAKMT2A | |
| SCHEMBL27386736 | 0.76 | ALDH1A1 (0.41) | ALDH1A1MAPTKDM4EPOLBLMNA | |
| SCHEMBL21546149 | 0.76 | EP300 (0.44) | ALDH1A1KDM4EEP300ADORA2B | |
| SCHEMBL7874474 | 0.74 | P2RX7 (0.37) | ALDH1A1MAPTKDM4EPOLBGAA | |
| SCHEMBL27696561 | 0.74 | EP300 (0.36) | EP300 | |
| SCHEMBL28402007 | 0.73 | EP300 (0.37) | ALDH1A1KDM4EEP300ADORA2BKMT2A | |
| SCHEMBL7639805 | 0.73 | KMT2A (0.55) | ALDH1A1MAPTPOLBGAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0792283-A1 | SYNTHESIS OF PEPTIDE NUCLEIC ACIDS (PNAs) AND ANALOGUES VIA SUBMONOMER APPROACH | CHIRON CORPORATION (US) | 1997-09-03 | — | — | EP | disclosed |
| WO-1996015143-A1 | SYNTHESIS OF PEPTIDE NUCLEIC ACIDS (PNAs) AND ANALOGUES VIA SUBMONOMER APPROACH | CHIRON CORPORATION (US) | 1996-05-23 | — | — | WO | disclosed |