Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 2/20 | 0.37 |
| ▸ | RIN1 | Q13671 | 2/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7867801 | 0.89 | MAPT (0.47) | MAPTRAB9ASCN9AABL1RIN1 | |
| SCHEMBL14310475 | 0.85 | MAPT (0.50) | MAPTRAB9ASCN9AABL1RIN1 | |
| SCHEMBL8581017 | 0.79 | RAB9A (0.57) | MAPTRAB9AABL1RIN1NPC1 | |
| SCHEMBL7635962 | 0.78 | DEGS1 (0.48) | MAPTRAB9ANPC1 | |
| SCHEMBL2153078 | 0.78 | RAB9A (0.63) | MAPTRAB9AABL1RIN1NPC1 | |
| SCHEMBL8299962 | 0.77 | MEN1 (0.45) | MAPTRAB9AABL1RIN1KMT2A | |
| SCHEMBL17390951 | 0.77 | MAPT (0.37) | MAPTRAB9ASCN9AABL1RIN1 | |
| SCHEMBL21226756 | 0.77 | TSHR (0.39) | PTGDR2P2RX7CNR2 | |
| SCHEMBL3141377 | 0.77 | RAB9A (0.43) | MAPTRAB9AABL1RIN1KMT2A | |
| SCHEMBL3136443 | 0.76 | ABL1 (0.53) | MAPTRAB9AABL1RIN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118858485-A | Method for detecting purity of 2- (4- ((tert-butoxycarbonyl) amino) -2-oxo pyrimidine-1 (2H) -yl) acetic acid | 上海吉奉生物科技有限公司 | 2024-10-29 | — | — | CN | claimed |
| CN-118858485-A | Method for detecting purity of 2- (4- ((tert-butoxycarbonyl) amino) -2-oxo pyrimidine-1 (2H) -yl) acetic acid | 上海吉奉生物科技有限公司 | 2024-10-29 | — | — | CN | disclosed |
| CN-118858485-A | Method for detecting purity of 2- (4- ((tert-butoxycarbonyl) amino) -2-oxo pyrimidine-1 (2H) -yl) acetic acid | 上海吉奉生物科技有限公司 | 2024-10-29 | — | — | CN | disclosed |
| CN-118858485-A | Method for detecting purity of 2- (4- ((tert-butoxycarbonyl) amino) -2-oxo pyrimidine-1 (2H) -yl) acetic acid | 上海吉奉生物科技有限公司 | 2024-10-29 | — | — | CN | disclosed |
| WO-2023039068-A1 | COMPOSITIONS AND METHODS FOR SYNTHESIS OF PEPTIDE NUCLEIC ACID INTERMEDIATES | NEUBASE THERAPEUTICS, INC. (US) | 2023-03-16 | — | — | WO | disclosed |
| US-20180282331-A1 | 7-Oxo -6-(sulfooxy)- 1,6-diazabicyclo [3.2.1] octane containing compounds and their use in treatment of bacterial infections (changed by PCT to: 7-OXO -6-(SULFOOXY)- 1,6-DIAZABICYCLO [3.2.1] OCTANE CONTAINING COMPOUNDS AND THEIR USE IN TREATMENT OF BACTERIAL INFECTIONS | WOCKHARDT LIMITED (IN) | 2018-10-04 | — | — | US | disclosed |
| EP-1873156-A1 | Process for the preparation of 6-[[(alkoxy)carbonyl]amino]-9H-Purine-9-acetic acid and 4-[(alkoxycarbonyl)amino]-2-oxo-1(2H)-Pyrimidineacetic acid derivatives as synthons for the synthesis of peptide nucleic acids | PerSeptive Biosystems, Inc. (US) | 2008-01-02 | — | — | EP | disclosed |
| US-6316595-B1 | PNA synthesis using a base-labile amino protecting group | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2001-11-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180282331-A1 | 7-Oxo -6-(sulfooxy)- 1,6-diazabicyclo [3.2.1] octane containing compounds and their use in treatment of bacterial infections (changed by PCT to: 7-OXO -6-(SULFOOXY)- 1,6-DIAZABICYCLO [3.2.1] OCTANE CONTAINING COMPOUNDS AND THEIR USE IN TREATMENT OF BACTERIAL INFECTIONS | TST, THPO, STS | MAPT 4620/4885RAB9A 3441/4885SCN9A 638/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.