SCHEMBL7874493

SCHEMBL7874493

C(OCC1CO1)C1CO1.FC(F)C(F)C(F)C(F)C(F)(F)C(F)(F)C(F)(F)C(F)CC1CO1

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.33
MAPK1 P28482 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3897150 0.76
SCHEMBL27727486 0.75 TSHR (0.37) TSHRMAPK1
SCHEMBL28557047 0.74 TSHR (0.41) TSHRMAPK1
SCHEMBL28416837 0.73 TSHR (0.50) TSHRMAPK1
SCHEMBL2332965 0.72 ALDH1A1 (0.32) TSHRMAPK1
SCHEMBL27748538 0.71 TSHR (0.39) TSHRMAPK1
SCHEMBL5077997 0.71 ALDH1A1 (0.31)
SCHEMBL10260036 0.70
SCHEMBL6396180 0.70 ALDH1A1 (0.30)
SCHEMBL1130097 0.69 TSHR (0.50) TSHRMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20010055461-A1 METHOD FOR PRODUCING AN OPTICAL WAVEGUIDE NIPPON TELEGRAPH AND TELEPHONE CORPORATION (JP) 2001-12-27 US disclosed
EP-0943935-A2 Optical waveguide and method for production thereof Nippon Telegraph and Telephone Corporation (JP) 1999-09-22 EP disclosed