Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27748538 | 0.87 | TSHR (0.39) | TSHRMAPK1ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL28557047 | 0.83 | TSHR (0.41) | TSHRMAPK1ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL28416837 | 0.78 | TSHR (0.50) | TSHRMAPK1ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL5187881 | 0.77 | ALDH1A1 (0.41) | TSHRMAPK1ALDH1A1 | |
| SCHEMBL28448363 | 0.75 | TSHR (0.43) | TSHRMAPK1ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL7874493 | 0.75 | TSHR (0.33) | TSHRMAPK1 | |
| SCHEMBL1130097 | 0.74 | TSHR (0.50) | TSHRMAPK1ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL3236704 | 0.74 | TSHR (0.54) | TSHRMAPK1ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL78818 | 0.74 | — | — | |
| SCHEMBL28448360 | 0.73 | TSHR (0.55) | TSHRMAPK1ALDH1A1SMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101353331-B | Fluorine-containing epoxide resin reactive diluent and preparation thereof | ZHONGHAO CHENGUANG RES INST CHEMICAL INDUSTRY | 2012-10-03 | — | — | CN | disclosed |
| CN-101353331-A | Fluorine-containing epoxide resin reactive diluent and preparation thereof | CHENGUANG RES INST OF CHEMICAL (CN) | 2009-01-28 | — | — | CN | disclosed |