SCHEMBL7874618

SCHEMBL7874618

C[O-].c1ccc(C[P+](c2ccccc2)(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SNCA P37840 2/20 0.59
HIF1A Q16665 1/20 0.50
TAAR1 Q96RJ0 4/20 0.43
SIGMAR1 Q99720 4/20 0.43
SLC6A2 P23975 2/20 0.43
MAOA P21397 1/20 0.43
SLC6A4 P31645 1/20 0.43
SLC6A3 Q01959 1/20 0.43
CYP2A6 P11509 1/20 0.43
ADORA2A P29274 1/20 0.43
ADORA1 P30542 1/20 0.43
CYP1A2 P05177 2/20 0.41
EPHX1 P07099 1/20 0.41
CYP2D6 P10635 2/20 0.40
TP53 P04637 1/20 0.40
SLC18A2 Q05940 1/20 0.40
TSHR P16473 2/20 0.39
ALDH1A1 P00352 1/20 0.39
CYP2C19 P33261 1/20 0.39
TRPA1 O75762 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29918368 0.93 SNCA (0.65) SNCAHIF1ATAAR1SIGMAR1SLC6A2
SCHEMBL7877298 0.91 SNCA (0.55) SNCAHIF1ATAAR1SIGMAR1SLC6A2
Hydrochloric Acid SCHEMBL494 0.90 SNCA (0.63) SNCAHIF1ATAAR1SIGMAR1SLC6A2
Fluoride Ion SCHEMBL585089 0.90 SNCA (0.63) SNCAHIF1ATAAR1SIGMAR1SLC6A2
Iodide SCHEMBL159922 0.90 SNCA (0.63) SNCAHIF1ATAAR1SIGMAR1SLC6A2
Water SCHEMBL3422802 0.90 SNCA (0.63) SNCAHIF1ATAAR1SIGMAR1SLC6A2
SCHEMBL989761 0.90 SNCA (0.63) SNCAHIF1ATAAR1SIGMAR1SLC6A2
Bromide SCHEMBL163158 0.90 SNCA (0.67) SNCAHIF1ATAAR1SIGMAR1SLC6A2
SCHEMBL8604262 0.88 SNCA (0.57) SNCAHIF1ATAAR1SIGMAR1SLC6A2
Perchlorate SCHEMBL2152691 0.88 SNCA (0.57) SNCAHIF1ATAAR1SIGMAR1SLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6316575-B1 MELT TRANSESTERIFICATION OF DIOL COMPOUND AND CARBOANTE COMPOUND USING CATALYST COMPRISING A PHOSPHORUS-CONTAINING BASIC COMPOUND QUATERNARY PHOSPHONIUM SALT TO FORM POLYCARBONATE IDEMITSU KOSAN CO., LTD. (JP) 2001-11-13 US claimed
US-4209643-A Preparation of acetals ETHYL CORPORATION (US) 1980-06-24 US disclosed