SCHEMBL8604262

SCHEMBL8604262

F[Zn-](F)F.c1ccc(C[P+](c2ccccc2)(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SNCA P37840 2/20 0.57
HIF1A Q16665 1/20 0.48
CYP1A2 P05177 2/20 0.40
EPHX1 P07099 1/20 0.39
CPA1 P15085 2/20 0.38
TSHR P16473 2/20 0.38
ALDH1A1 P00352 2/20 0.38
CYP2D6 P10635 1/20 0.38
CYP2C19 P33261 1/20 0.38
SLC6A2 P23975 2/20 0.37
TAAR1 Q96RJ0 2/20 0.37
MAOA P21397 1/20 0.37
SLC6A4 P31645 1/20 0.37
SLC6A3 Q01959 1/20 0.37
SIGMAR1 Q99720 1/20 0.37
CYP2A6 P11509 1/20 0.37
ADORA2A P29274 1/20 0.37
ADORA1 P30542 1/20 0.37
CYP3A4 P08684 1/20 0.36
CALM1 P0DP23 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29918368 0.91 SNCA (0.65) SNCAHIF1ACYP1A2EPHX1CPA1
SCHEMBL7874618 0.88 SNCA (0.59) SNCAHIF1ACYP1A2EPHX1TSHR
Water SCHEMBL3422802 0.88 SNCA (0.63) SNCAHIF1ACYP1A2EPHX1CPA1
Fluoride Ion SCHEMBL585089 0.88 SNCA (0.63) SNCAHIF1ACYP1A2EPHX1CPA1
Hydrochloric Acid SCHEMBL494 0.88 SNCA (0.63) SNCAHIF1ACYP1A2EPHX1CPA1
SCHEMBL989761 0.88 SNCA (0.63) SNCAHIF1ACYP1A2EPHX1CPA1
Iodide SCHEMBL159922 0.88 SNCA (0.63) SNCAHIF1ACYP1A2EPHX1CPA1
Bromide SCHEMBL163158 0.88 SNCA (0.67) SNCAHIF1ACYP1A2EPHX1CPA1
SCHEMBL22463127 0.86 SNCA (0.57) SNCAHIF1ACYP1A2EPHX1CPA1
SCHEMBL8374374 0.86 SNCA (0.57) SNCAHIF1ACYP1A2EPHX1CPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0718707-B1 Quaternary phosphonium trihalozincate salts as charge-control agents for toners and developers EASTMAN KODAK CO (US) 1998-03-04 EP disclosed
US-5561020-A THERMALLY STABLE, UNIFORMLY DISPERSIBLE EASTMAN KODAK COMPANY (US) 1996-10-01 US disclosed
EP-0718707-A1 Quaternary phosphonium trihalozincate salts as charge-control agents for toners and developers EASTMAN KODAK COMPANY (US) 1996-06-26 EP disclosed